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Home > Graduate School of Medicine > Bio-Information Medicine
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Doctor Course, Graduate School of Medicine

Bio-Information Medicine
Field Faculty Research Field
Informative
and
Preventive
Science

Neural Transmission Informatics

Fumiyo Toyoda

  1. Electrical signaling in retinal development
  2. Synaptic transmission in hippocampus
  3. Pheromonal and hormonal control of behavior
  4. Mechanism of spatial orientation
  5. Physiological effects of odor

Clinical Laboratory Medicine


Masaharu Yamazaki

  1. Analysis of genetic mutation and polymorphism
  2. Analysis of protein function and molecular abnormality
  3. Computer-assisted data analysis and diagnosis
Biomacromolecules



Hiromi SAKAI

Keizo YAMAMOTO

  1. Design and synthesis of artificial red cells and transfusion alternatives
  2. In vivo efficacy evaluation of artificial red cells.
  3. New clinical application of artificial red cells New application of artificial red cells.
  4. Study on new micro-and nano-encapsulation
  5. Purification and chemical modification of biomacromolecules
  6. X-ray crystallography and functional evaluation of proteins
  7. Study on new materials for biomedical application
Bioprotection and Regeneration Medicine


Masahide Yoshikawa
  1. Reserch on ES/iPS cell differentiation – Induction of hepatocytes , insulin-producing cells, dopamine producing cells, inner ear hair cells, etc.–
  2. Cell transplantation therapies for spinal cord injury, Parkinson’s disease, liver diseases, diabetes mellitus, and deafness
  3. Regenerative medicine using bone marrow mesenchymal stem cells and skin stem cells
  4. Analysis of signal transduction in trichogenesis
Clinical Diagnostic Pathology


Chiho Ohbayashi
  1. Pathological studies using human surgical and autopsy specimens
    • Histologic and morphologic study
    • Clinicopathological study
    • Immunohistochemical study
    • Molecular study
  2. Study of desquamated and aspiration cytology
    • Morphological study
    • Immunohistochemical study
    • Molecular study
Emergency Medical Science

Kazuo Okuchi


  1. Therapeutic method for organ failure due to hemorrhagic shock
  2. Burn reconstruction using cultured epithelial autograft
  3. Electrophysiological and neuroradiological stud for CPA
  4. Study for cardiac dysfuction after SAH
  5. Study for cytokines m-RNA in acute respiratory failure
  6. Anatomical and mechanical study for unstable pelvic fracture
  7. Study for cardiopulmpnary resuscitation in prehospital patients 
  8. Study for pulmonary capillary permeability in septic shock
  9. Blood coagulation in emergency medical field
  10. Study for cerebral oxygen metabolism using near-infra red device
Anesthesiology and Pain Medicine

Masahiko Kawaguchi
  1. Study on cerebral and spinal cord protection
  2. Study on cerebral and spinal cord monitoring
  3. Study on postoperative complications
  4. Study on safety and quality of perioperative managements
  5. Study on airway managements
  6. Study on pain management for cancer patients
  7. Study on chronic pain management
Signal Transduction in Pharmacology

Masanori Yoshizumi
  1. Explore the role of oxidative stress in the progression of atherosclerosis
  2. Development of new drugs for atherosclerosis from natural food nutrients
  3. Mechanisms of vasoactive substance-induced vascular remodeling in hypertension and atherosclerosis
  4. Investigation into the molecular mechanisms and pharmacological intervention for angiogenesis
  5. Analysis of intracellular signal transduction of insulin resistance in vascular smooth muscle cells
  6. Explore the role of oxidative stress in the progression of neurodegenerative diseases
  7. Protein S-nytorsylation and diseases
  8. Investigation into the mechanisms of intracellular signal transduction in neural type nicotinic acetylcholine receptor 
Infectious Diseases


Keiichi Mikasa
  1. Research on interaction between host and microorganism in infectious diseases
  2. Research on host defense and its control in respiratory tract infection
  3. Research on biological activity of antimicrobial agents against resistant bacteria
  4. Research on pathogenesis and treatment of HIV infection
  5. Research on early diagnosis and multidisciplinary treatment of deep-seated fungal diseases
  6. Research on molecular epidemiology of drug resistant bacteria
  7. Research on appropriate use of antimicrobial agents
Molecular Biology of Neural System

AkioTsuboi  
  1. Molecular mechanism for formation and reformation of neural circuits in the olfactory system
  2. Regulatory mechanism of adult neurogenesis in the olfactory system
  3. Molecular mechanism for organizing the olfactory sensory map in the brain
  4. Strategy for the gene expression specific to olfactory neurons by the lentiviral system
  5. Molecular mechanism for sensing food oils by olfaction
  6. Molecular mechanism for sensing CO2 by the mammalian olfaction
  7. Regenerative therapy for the central nerve injury such as cerebral ischemia
Organo-
Pathologic Science
Gastroenterology, Endocrinology and Metabolism

Hiroshi Fukui
  1. Pathophysiology of ascites and spontaneous bacterial peritonitis
  2. Endotoxin, innate immunity and digestive diseases
  3. ADAMTS13 abnormality in liver, biliary and pancreatic diseases
  4. Liver regeneration (from embryonic stem cells to hepatic stem cells)
  5. Pathophysiology of nonalcoholic steatohepatitis
  6. Anti-angiogenesis treatment for hepatocellular carcinoma
  7. Pathophysiology of liver fibrosis
  8. Pathophysiology and treatment of acute hepatic failure
  9. Liver transporter in liver diseases
  10. Pathophysiology of digestive and liver disorders in the elderly
Respiratory And Hematology Medicine


Hiroshi Kimura


Kaoru Hamada


Masanori Yoshikawa
  1. Pathogenesis and mechanisms of airway remodeling / pulmonary vascular remodeling
  2. Regenerative medicine in epithelial and endothelial cells of the lung in patients with pulmonary emphysema
  3. Analyses on genetic and nutritional factors and development of therapeutic strategy for patients with COPD
  4. Pathogenesis and the therapeutic strategy for refractory pulmonary hypertension
  5. Analyses of the pathogenesis and mechanisms of chronic thromboembolic pulmonary hypertension
  6. Molecular mechanisms of the hypoxia-reoxygenation injury in patients with sleep disordered breathing
  7. Molecular mechanisms of the role of chemokines and dendritic cells on the infectious pulmonary diseases
  8. The role of air-pollution on the molecular mechanisms of airway remodeling of bronchial asthma
  9. The role of chemokines and dendritic cells in theautoimmune and allergic diseases
  10. Molecular mechanisms of hypoxic stress during sleep in patients with metabolic syndrome
  11. Molecular mechanisms of growth and progression in lung cancer
  12. Construction of the gtailor-made therapyh for lung cancer
  13. Development of the new therapeutic strategy with dendritic cells
  14. Regulation of immune response after hematopoietic stem cell trasplantation
  15. Functionnal analysis of actication antigen CD69
  16. The role of trace elements on hematopoietic diseases
Cardiorenal Medicine


Yoshihiko Saito


ShiroUemura

  1. Prevention of cardiovascular diseases in accordance with genetic risk factors
  2. Investigation of molecular mechanism for heart failure
  3. Development of therapeutic angiogenesis in ischemic limb and cardiomyopathy
  4. Development of a novel thrombolytic therapy in combination with ultrasound for acute myocardial infarction
  5. Molecular biological approach for prevention of coronary artery stenosis
  6. Investigation of the molecular mechanism for heart failure-related ventricular arrhythmia
  7. Molecular biological approach for inhibition of expansion of infarct size
  8. Investigation of the molecular mechanism for cardiovascular complication in diabetes mellitus
  9. Investigation of the molecular mechanism of vascular complications in renal failure
  10. Investigation of the molecular mechanism for renal interstitial fibrosis
  11. Epidemiological study for cardiovascular events in DM

Ophthalmology and Vision Science

Nahoko Ogata

Toyoaki Matuura

  1. Mechanism of pseudoaccommodation
  2. Studies of E.R.G., V.E.P
  3. Refractive Surgery
  4. Studies of corneal epithelium and cytokine
  5. Development of accommodative intraocular lens
  6. Studies of phase transition
  7. Studies of dynamic laser scattering of ocular tissue
  8. Studies of ocular aberration
  9. Mechanism of age-related macular degeneration
  10. Studies of clinical treatment on age-related macular degeneration
  11. Mechanism of diabetic retinopathy
  12. Studies of clinical treatment on diabetic retinopathy
  13. Studies of neuroprotection
  14. Studies of ocular blood flow
  15. Cohort studies of visual acuity on aged people
Obstetrics, Gynecology and Reproductive Medicine


Hiroshi Kobayashi


Hidekazu Ooi


  1. Translational Research for Gynecological Cancers by Anti-Metastatic Compounds
  2. Ant-Metastasis Gene Therapy for Patients with Ovarian Cancer
  3. Drug Delivery System of Anti-Metastatic Compound by Computer Analysis
  4. Mechanism of Metastasis of Gynecological Cancers
  5. Gene Profiling of Chemo-Resistance in Gynecological Cancer
  6. Gene Profiling of Development of Endometriosis-Associated Ovarian Cancer
  7. Gene Profiling of Familiar Endometrial Cancer
  8. Establishment of Criteria for Adenoma Malignumof the Uterine Cervix
  9. Prediction and Screening for Early-stage Ovarian Cancer
  10. Epidemiology of Venous Thromboembolism in Pregnancy and Puerperium
  11. Prediction of Premature Delivery using Biomarkers
  12. Establishment of Standard for Prediction of Premature Delivery
  13. Pathophysiology of Twin to Twin Transfusion Syndrome
  14. Establishment of Criteria for Pulmonary Embolism by Surface Plasmon Resonance
  15. A Cohort Study for Pregnancy, Lactation and Medicine
  16. A Cohort Study for Cytomegarovirus Infection in Pregnancy
  17. Study for Pathophysiology of Preeclampsia and Fetal Growth and Development in Preeclampsia Patients
  18. Development of a novel feto-maternal monitoring system
Dermatology

Hideo Asada

  1. Studies on innate immunity in atopic dermatitis
  2. Studies on pathogenic role for viral infection in allergic skin diseases
  3. Studies on pathogenic mechanism of severe drug eruption
  4. Mechanism in carcinogenesis of EB virus-associated malignant lymphoma
  5. Development of herpes zoster vaccine
  6. Studies on skin damage by ultraviolet light
  7. Studies on skin and hair regeneration
  8. Molecular-biological research on pathogenic mechanism of hypertrophic scar
  9. Pathological analysis of skin tumor to find new diagnostic procedure
  10. Application of ultrasound to the diagnosis of skin diseases



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