原著論文

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原著(2020年)

1. Koshiro Kanaoka, Satoshi Okayama,  Satoshi Terasaki, Tomoya Nakano, Masanobu Ishii, Michikazu Nakai, Kenji Onoue, Kunihiro Nishimura, Satoshi Yasuda, Kenichi Tsujita, Rika Kawakami, Yoshihiro Miyamoto, Hiroyuki Tsutsui, Issei Komuro, Hisao Ogawa, Yoshihiko Saito.
Role of Climatic Factors in the Incidence of Takotsubo Syndrome: A Nationwide Study from 2012 to 2016
ESC Heart Fail (in press)
2. Nogi M, Kawakami R, Ishihara S, Hirai K, Nakada Y, Nakagawa H, Ueda T, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Saito Y.
Low Insulin Is an Independent Predictor of All-Cause and Cardiovascular Death in Acute Decompensated Heart Failure Patients Without Diabetes Mellitus.
J Am Heart Assoc. 2020 May 18;9(10)
3. Soejima H, Ogawa H, Morimoto T, Okada S, Matsumoto C, Nakayama M, Masuda I, Jinnouchi H, Waki M, Saito Y; JPAD Trial Investigators.
Proteinuria is independently associated with the incidence of primary cardiovascular events in diabetic patients.
J Cardiol. 2020 Apr;75(4):387-393.
4. Ishihara S. Kawakami R. Nogi M. Hirai K. Hashimoto Y. Nakada Y. Nakagawa H. Ueda T. Nishida T. Onoue K. Soeda T. Okayama S. Watanabe M. Saito Y.
Incidence and Clinical Significance of 30-day and 90-day Rehospitalization for Heart Failure among Patients with Acute Decompensated Heart Failure in Japan: From the NARA-HF Study.
Circ J. 2020 Jan 24;84(2):194-202.

 

共同研究(2020年)

1. Matsuzawa Y, Konishi M, Nakai M, Saigusa Y, Taguri M, Gohbara M, Ebina T, Kosuge M, Hibi K, Nishimura K, Miyamoto Y, Yasuda S, Ogawa H, Saito Y, Nakayama N, Takeuchi I, Tamura K, Kimura K.
In-Hospital Mortality in Acute Myocardial Infarction According to Population Density and Primary Angioplasty Procedures Volume.
Circ J. 2020 May 27.
2. Mika Watanabe, Kihei Yoneyama, Michikazu Nakai, Koshiro Kanaoka, Satoshi Okayama, Kunihiro Nishimura, Yoshihiro Miyamoto, Masaki Izumo, Yuki Ishibashi, Takumi Higuma, Tomoo Harada, Satoshi Yasuda, Toyoaki Murohara, Yoshihiko Saito, Yoshihiro J. Akashi
Impact of Board-Certified Cardiologist Characteristics on Risk of In-Hospital Mortality.
Circ Rep 2020; 2: 44–50
3. Konishi M, Matsuzawa Y, Ebina T, Kosuge M, Gohbara M, Nishimura K, Nakai M, Miyamoto Y, Saito Y, Tsutsui H, Komuro I, Ogawa H, Tamura K, Kimura K.
Impact of population density on mortality in patients hospitalized for heart failure - JROAD-DPC Registry Analysis.
J Cardiol. 2020 Apr;75(4):447-453.
4. Kasahara M, Kuwabara Y, Moriyama T, Tanabe K, Satoh-Asahara N, Katsuya T, Hiramitsu S, Shimada H, Sato T, Saito Y, Nakagawa T.
Intensive uric acid-lowering therapy in CKD patients: the protocol for a randomized controlled trial.
Clin Exp Nephrol. 2020 Mar;24(3):235-241.
5. Ishii M, Kaikita K, Sakamoto K, Seki T, Kawakami K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Noguchi T, Yasuda S, Tsutsui H, Komuro I, Saito Y, Ogawa H, Tsujita K; JROAD Investigators.
Characteristics and in-hospital mortality of patients with myocardial infarction in the absence of obstructive coronary artery disease in super-aging society.
Int J Cardiol. 2020 Feb 15;301:108-113.
6. Matsumoto C, Ogawa H, Saito Y, Okada S, Soejima H, Sakuma M, Masuda I, Nakayama M, Doi N, Jinnouchi H, Waki M, Morimoto T; JPAD Trial Investigators; JPAD Trial Investigators:.
Sex Difference in Effects of Low-Dose Aspirin on Prevention of Dementia in Patients With Type 2 Diabetes: A Long-term Follow-up Study of a Randomized Clinical Trial.
Diabetes Care. 2020 Feb;43(2):314-320.
7. Oikawa M, Yoshihisa A, Sato Y, Nagai T, Yoshikawa T, Saito Y, Yamamoto K, Takeishi Y, Anzai T.
Prognostic impact of moderate mitral regurgitation on hospitalized heart failure patients with preserved ejection fraction: A report from the JASPER registry.
Heart Vessels. 2020 Mar 19.
8. Ishii M, Seki T, Kaikita K, Sakamoto K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Noguchi T, Yasuda S, Tsutsui H, Komuro I, Saito Y, Ogawa H, Tsujita K, Kawakami K; JROAD Investigators.
Short-term exposure to desert dust and the risk of acute myocardial infarction in Japan: a time-stratified case-crossover study.
Eur J Epidemiol. 2020 Jan 16.
9. Fujino N, Furusho H, Sakata K, Onoue K, Chiang DY, Kiviniemi TO, Buys E, Sips P, Burch ML, Zhao Y, Kelly AE, Namura M, Kita Y, Tsuchiya T, Kaku B, Oe K, Takeda Y, Konno T, Inoue M, Fujita T, Kato T, Funada A, Tada H, Hodatsu A, Nakanishi C, Sakamoto Y, Tsuda T, Nagata Y, Tanaka Y, Okada H, Usuda K, Cui S, Saito Y, MacRae CA, Takashima S, Yamagishi M, Kawashiri MA, Takamura M.
Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases.
Hayashi K, Teramoto R, Nomura A, Asano Y, Beerens M, Kurata Y, Kobayashi I, Cardiovasc Res. 2020 Jan 24.
10. Temma T, Nagai T, Watanabe M, Kamada R, Takahashi Y, Hagiwara H, Koya T, Nakao M, Omote K, Kamiya K, Iwano H, Yamamoto K, Yoshikawa T, Saito Y, Anzai T.
Differential Prognostic Impact of Atrial Fibrillation in Hospitalized Heart Failure Patients With Preserved Ejection Fraction According to Coronary Artery Disease Status - Report From the Japanese Nationwide Multicenter Registry.
Circ J. 2020 Feb 1.
11. Takemura G, Onoue K, Arimoto T, Watanabe T, Tsujimoto A, Takada C, Okada H, Nakano T, Sakaguchi Y, Miyazaki N, Watanabe T, Kanamori H, Ogura S, Saito Y, Fujiwara T, Fujiwara H, Hotta Y.
Vacuolated cardiomyocytes in human endomyocardial biopsy specimens.
J Cardiol Cases. 2019 Oct 7;21(2):54-58.
12. Noguchi T, Yasuda S, Kanaoka K, Terasaki S, Saito Y, Tsutsui H, Komuro I, Ogawa H, Tsujita K, Kawakami K; on the behalf of the JROAD Investigators.
Association of short-term exposure to air pollution with myocardial infarction with and without obstructive coronary artery disease.
Ishii M, Seki T, Kaikita K, Sakamoto K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Eur J Prev Cardiol. 2020 Feb 11:

原著(2019年)

2. Kamon D, Okura H, Okamura A, Nakada Y, Hashimoto Y, Sugawara Y, Ueda T, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Kawakami R, Saito Y.
Plasma Renin Activity Is an Independent Prognosticator in Patients With Myocardial Infarction.
Circ J. 2019 Apr 20.
3. Kanaoka K, Okayama S, Nakai M, Sumita Y, Nishimura K, Kawakami R, Okura H, Miyamoto Y, Yasuda S, Tsutsui H, Komuro I, Ogawa H, Saito Y.
Hospitalization Costs for Patients With Acute Congestive Heart Failure in Japan.
Circ J. 2019 Apr 25;83(5):1025-1031.
4. Kanaoka K, Okayama S, Nakai M, Sumita Y, Onoue K, Soeda T, Nishimura K, Kawakami R, Okura H, Miyamoto Y, Yasuda S, Tsutsui H, Komuro I, Ogawa H, Saito Y.
Number of Cardiologists per Cardiovascular Beds and In-Hospital Mortality for Acute Heart Failure: A Nationwide Study in Japan.
J Am Heart Assoc. 2019 Sep 17;8(18):
5. Nakada Y, Kawakami R, Matsui M, Ueda T, Nakano T, Nakagawa H, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Okura H, Saito Y.
Value of Placental Growth Factor as a Predictor of Adverse Events During the Acute Phase of Acute Decompensated Heart Failure.
Circ J. 2019 Jan 25;83(2):395-400.
6. Nakada Y, Kawakami R, Matsushima S, Ide T, Kanaoka K, Ueda T, Ishihara S, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Okura H, Tsuchihashi-Makaya M, Tsutsui H, Saito Y.
Simple Risk Score to Predict Survival in Acute Decompensated Heart Failure - A 2 B Score.
Circ J. 2019 Mar 7.
7. Nakada Y, Onoue K, Nakano T, Ishihara S, Kumazawa T, Nakagawa H, Ueda T, Nishida T, Soeda T, Okayama S, Watanabe M, Kawakami R, Saito Y.
AST-120, an Oral Carbon Absorbent, Protects against the Progression of Atherosclerosis in a Mouse Chronic Renal Failure Model by Preserving sFlt-1 Expression Levels.
Sci Rep. 2019 Oct 30;9(1):15571.
8. Nogi Kazutaka, Shiraishi Atsushi, Yamamoto Ryohei, Sasano Mikio, Matsumoto Takashi, Karumai Toshiyuki, Hayashi Yoshiro.
Intermittent Hemodialysis for Managing Metabolic Acidosis During Resuscitation of Septic Shock: A Descriptive Study.
Critical Care Explorations: December 2019 - Volume 1 - Issue 12.
9. Okura H, Nakada Y, Ishihara S, Nogi M, Onoue K, Soeda T, Okayama S, Watanabe M, Kawakami R, Saito Y.
"Hidden" takotsubo cardiomyopathy in cardiac care unit.
J Echocardiogr. 2019 Dec 13.
10. Onoue K, Takemura G, Nakano T, Miyazaki N, Tsujimoto A, Watanabe T, Okada H, Kanamori H, Sugiura J, Kanaoka K, Ishihara S, Horii M, Akai Y, Sakaguchi Y, Saito Y.
Ultrastructural Evidence of Glycosphingolipid Degradation After Enzyme Replacement Therapy in Patients With Fabry Disease.
Circ J. 2019 Mar 29.
11. Soejima H, Ogawa H, Morimoto T, Okada S, Sakuma M, Nakayama M, Masuda I, Doi N, Uemura S, Jinnouchi H, Sugiyama S, Waki M, Saito Y; JPAD Trial Investigators.
One quarter of total myocardial infarctions are silent manifestation in patients with type 2 diabetes mellitus.
J Cardiol. 2019 Jan;73(1):33-37.
12. Takemura G, Onoue K, Nakano T, Nakamura T, Sakaguchi Y, Tsujimoto A, Miyazaki N, Watanabe T, Kanamori H, Okada H, Kawasaki M, Fujiwara T, Fujiwara H, Saito Y.
Possible mechanism for disposal of degenerative cardiomyocytes in human failing hearts: phagocytosis by a neighbour.
ESC Heart Fail. 2019 Feb;6(1):208-216.
13. Ueda T, Kawakami R, Nakada Y, Nakano T, Nakagawa H, Matsui M, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Okura H, Saito Y.
Differences in blood pressure riser pattern in patients with acute heart failure with reduced mid-range and preserved ejection fraction.
ESC Heart Fail. 2019 Jul 19.

 

共同研究(2019年)

1. Ishii M, Kaikita K, Sakamoto K, Seki T, Kawakami K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Noguchi T, Yasuda S, Tsutsui H, Komuro I, Saito Y, Ogawa H, Tsujita K; JROAD Investigators.
Characteristics and in-hospital mortality of patients with myocardial infarction in the absence of obstructive coronary artery disease in super-aging society.
Int J Cardiol. 2019 Oct 25.
2. Kamiya K, Yamamoto T, Tsuchihashi-Makaya M, Ikegame T, Takahashi T, Sato Y, Kotooka N, Saito Y, Tsutsui H, Miyata H, Isobe M.
Nationwide Survey of Multidisciplinary Care and Cardiac Rehabilitation for Patients With Heart Failure in Japan - An Analysis of the AMED-CHF Study.
Circ J. 2019 Jun 25;83(7):1546-1552.
3. Kasahara M, Kuwabara Y, Moriyama T, Tanabe K, Satoh-Asahara N, Katsuya T, Hiramitsu S, Shimada H, Sato T, Saito Y, Nakagawa T.
Intensive uric acid-lowering therapy in CKD patients: the protocol for a randomized controlled trial.
Clin Exp Nephrol. 2019 Nov 15.
4. Kobayashi Y, Omote K, Nagai T, Kamiya K, Konishi T, Sato T, Kato Y, Komoriyama H, Tsujinaga S, Iwano H, Yamamoto K, Yoshikawa T, Saito Y, Anzai T.
Prognostic Value of Serum Uric Acid in Hospitalized Heart Failure Patients With Preserved Ejection Fraction (from the Japanese Nationwide Multicenter Registry).
Am J Cardiol. 2019 Dec 9.
5. Kojima S, Matsui K, Hiramitsu S, Hisatome I, Waki M, Uchiyama K, Yokota N, Tokutake E, Wakasa Y, Jinnouchi H, Kakuda H, Hayashi T, Kawai N, Mori H, Sugawara M, Ohya Y, Kimura K, Saito Y, Ogawa H; Febuxostat for Cerebral and CaRdiorenovascular Events PrEvEntion StuDy (FREED) investigators.
Febuxostat for Cerebral and CaRdiorenovascular Events PrEvEntion StuDy.
Eur Heart J. 2019 Mar 7.
6. Konishi M, Matsuzawa Y, Ebina T, Kosuge M, Gohbara M, Nishimura K, Nakai M, Miyamoto Y, Saito Y, Tsutsui H, Komuro I, Ogawa H, Tamura K, Kimura K.
Impact of population density on mortality in patients hospitalized for heart failure - JROAD-DPC Registry Analysis.
J Cardiol. 2019 Oct 9. pii: S0914-5087(19)30298-9.
7. Marume K, Takashio S, Nagai T, Tsujita K, Saito Y, Yoshikawa T, Anzai T.
Effect of Statins on Mortality in Heart Failure With Preserved Ejection Fraction Without Coronary Artery Disease - Report From the JASPER Study.
Circ J. 2019 Jan 25;83(2):357-367.
8. Matsumoto C, Ogawa H, Saito Y, Okada S, Soejima H, Sakuma M, Masuda I, Nakayama M, Doi N, Jinnouchi H, Waki M, Morimoto T; JPAD Trial Investigators; JPAD Trial Investigators.
Sex Difference in Effects of Low-Dose Aspirin on Prevention of Dementia in Patients With Type 2 Diabetes: A Long-term Follow-up Study of a Randomized Clinical Trial.
Diabetes Care. 2019 Dec 4.
9. Nakao K, Yasuda S, Nishimura K, Noguchi T, Nakai M, Miyamoto Y, Sumita Y, Shishido T, Anzai T, Ito H, Tsutsui H, Saito Y, Komuro I, Ogawa H.
Prescription Rates of Guideline-Directed Medications Are Associated With In-Hospital Mortality Among Japanese Patients With Acute Myocardial Infarction: A Report From JROAD - DPC Study.
J Am Heart Assoc. 2019 Apr 2;8(7):
10. Ogata S, Nishimura K, Guzman-Castillo M, Sumita Y, Nakai M, Nakao YM, Nishi N, Noguchi T, Sekikawa A, Saito Y, Watanabe T, Kobayashi Y, Okamura T, Ogawa H, Yasuda S, Miyamoto Y, Capewell S, O'Flaherty M.
Explaining the decline in coronary heart disease mortality rates in Japan: Contributions of changes in risk factors and evidence-based treatments between 1980 and 2012.
Int J Cardiol. 2019 Feb 14. pii: S0167-5273(18)34148-2.
11. Okuno K, Naito Y, Asakura M, Sugahara M, Ando T, Yasumura S, Nagai T, Saito Y, Yoshikawa T, Masuyama T, Anzai T.
Effective blood hemoglobin level to predict prognosis in heart failure with preserved left ventricular ejection fraction: results of the Japanese heart failure syndrome with preserved ejection fraction registry.
Heart Vessels. 2019 Jan 24.
12. Okuno T, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Tobaru T, Saku K, Ohshima S, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET Investigators.
Admission Heart Rate Is a Determinant of Effectiveness of Beta-Blockers in Acute Myocardial Infarction Patients.
Circ J. 2019 Apr 25;83(5):1054-1063.
13. Okuno T, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Tobaru T, Saku K, Ohshima S, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET investigators.
Association of onset-season with characteristics and long-term outcomes in acute myocardial infarction patients: results from the Japanese registry of acute myocardial infarction diagnosed by universal definition (J-MINUET) substudy.
Heart Vessels. 2019 May 25.
14. Omote K, Nagai T, Iwano H, Tsujinaga S, Kamiya K, Aikawa T, Konishi T, Sato T, Kato Y, Komoriyama H, Kobayashi Y, Yamamoto K, Yoshikawa T, Saito Y, Anzai T.
Left ventricular outflow tract velocity time integral in hospitalized heart failure with preserved ejection fraction.
ESC Heart Fail. 2019 Dec 18.
15. Omote K, Nagai T, Kamiya K, Aikawa T, Tsujinaga S, Kato Y, Komoriyama H, Iwano H, Yamamoto K, Yoshikawa T, Saito Y, Anzai T.
Long-term Prognostic Significance of Admission Tricuspid Regurgitation Pressure Gradient in Hospitalized Patients With Heart Failure With Preserved Ejection Fraction: A Report From the Japanese Real-World Multicenter Registry.
J Card Fail. 2019 Jul 22.
16. Sato Y, Yoshihisa A, Oikawa M, Nagai T, Yoshikawa T, Saito Y, Yamamoto K, Takeishi Y, Anzai T.
Hyponatremia at discharge is associated with adverse prognosis in acute heart failure syndromes with preserved ejection fraction: a report from the JASPER registry.
Eur Heart J Acute Cardiovasc Care. 2019 Jan 22.
17. Sato Y, Yoshihisa A, Oikawa M, Nagai T, Yoshikawa T, Saito Y, Yamamoto K, Takeishi Y, Anzai T.
Prognostic impact of worsening renal function in hospitalized heart failure patients with preserved ejection fraction -A report from the JASPER Registry.
J Card Fail. 2019 Apr 17.
18. Sato Y, Yoshihisa A, Oikawa M, Nagai T, Yoshikawa T, Saito Y, Yamamoto K, Takeishi Y, Anzai T.
Relation of Systolic Blood Pressure on the Following Day with Post-Discharge Mortality in Hospitalized Heart Failure Patients with Preserved Ejection Fraction.
Int Heart J. 2019 Jun 28.
19. Soejima H, Ogawa H, Morimoto T, Okada S, Matsumoto C, Nakayama M, Masuda I, Jinnouchi H, Waki M, Saito Y; JPAD Trial Investigators.
Proteinuria is independently associated with the incidence of primary cardiovascular events in diabetic patients.
J Cardiol. 2019 Sep 26. pii: S0914-5087(19)30283-7.
20. Sugiyama T, Yamamoto E, Fracassi F, Lee H, Yonetsu T, Kakuta T, Soeda T, Saito Y, Yan BP, Kurihara O, Takano M, Niccoli G, Crea F, Higuma T, Kimura S, Minami Y, Ako J, Adriaenssens T, Boeder NF, Nef HM, Fujimoto JG, Fuster V, Finn AV, Falk E, Jang IK.
Calcified Plaques in Patients With Acute Coronary Syndromes.
JACC Cardiovasc Interv. 2019 Mar 25;12(6):531-540.
21. Tsutsui H, Momomura SI, Masuyama T, Saito Y, Komuro I, Murohara T, Kinugawa S; CIBIS-J Investigators.
Tolerability, Efficacy, and Safety of Bisoprolol vs. Carvedilol in Japanese Patients With Heart Failure and Reduced Ejection Fraction - The CIBIS-J Trial.
Circ J. 2019 Apr 6.
22. Tsutsui H, Momomura SI, Yamashina A, Shimokawa H, Kihara Y, Saito Y, Hagiwara N, Ito H, Yano M, Yamamoto K, Ako J, Inomata T, Sakata Y, Tanaka T, Kawasaki Y; J-SHIFT Study Investigators.
Efficacy and Safety of Ivabradine in Japanese Patients With Chronic Heart Failure - J-SHIFT Study.
Circ J. 2019 Aug 8.
23. Uemura S, Okamoto H, Nakai M, Nishimura K, Miyamoto Y, Yasuda S, Tanaka N, Kohsaka S, Kadota K, Saito Y, Tsutsui H, Komuro I, Ikari Y, Ogawa H, Nakamura M.
Primary Percutaneous Coronary Intervention in Elderly Patients With Acute Myocardial Infarction - An Analysis From a Japanese Nationwide Claim-Based Database.
Circ J. 2019 May 24;83(6):1229-1238.
24. Yamamoto E, Yonetsu T, Kakuta T, Soeda T, Saito Y, Yan BP, Kurihara O, Takano M, Niccoli G, Higuma T, Kimura S, Minami Y, Ako J, Adriaenssens T, Boeder NF, Nef HM, Fracassi F, Sugiyama T, Lee H, Crea F, Kimura T, Fujimoto JG, Fuster V, Jang IK.
Clinical and Laboratory Predictors for Plaque Erosion in Patients With Acute Coronary Syndromes.
J Am Heart Assoc. 2019 Nov 5;8(21):e012322.
25. Yoneyama K, Kanaoka K, Okayama S, Nishimura K, Nakai M, Matsushita K, Miyamoto Y, Kida K, Ishibashi Y, Izumo M, Watanabe M, Soeda T, Okura H, Harada T, Yasuda S, Murohara T, Ogawa H, Saito Y, Akashi YJ.
Association between the number of board-certified cardiologists and the risk of in-hospital mortality: a nationwide study involving the Japanese registry of all cardiac and vascular diseases.
BMJ Open. 2019 Dec 15;9(12).

原著(2018年)

1. Goryo Y, Kume T, Ueda T, Watanabe M, Yamada R, Neishi Y, Saito Y, Uemura S.
Vascular Healing Response after Everolimus-Eluting Stent Implantation in Acute Coronary Syndrome Culprit Lesions: Comparison with Implantation in Stable Angina Pectoris.
Acta Cardiol Sin. 2018 Mar;34(2):124-129.
2. Ishihara S, Kioka H, Ohtani T, Asano Y, Yamaguchi O, Hikoso S, Toda K, Saito Y, Sawa Y, Yamauchi-Takihara K, Sakata Y.
Successful treatment of severe combined post- and pre-capillary pulmonary hypertension in a patient with idiopathic restrictive cardiomyopathy.
Pulm Circ. 2018 Jul-Sep;8(3)
3. Kanaoka K, Horii M, Nagato H, Kaneda K.
A giant pulmonary artery aneurysm.
Eur Heart J Cardiovasc Imaging. 2018 Feb 1;19(2):236.
5. Kanaoka K, Nishida T.
Successful pulmonary vein isolation by ablation in the right atrium.
J Cardiovasc Electrophysiol. 2018 Mar;29(3):483-484.
6. Kanaoka K, Okayama S, Yoneyama K, Nakai M, Nishimura K, Kawata H, Horii M, Kawakami R, Okura H, Miyamoto Y, Akashi Y, Saito Y.
Number of Board-Certified Cardiologists and Acute Myocardial Infarction-Related Mortality in Japan - JROAD and JROAD-DPC Registry Analysis.
Circ J. 2018 Sep 12
7. Nakada Y, Kawakami R, Matsui M, Ueda T, Nakano T, Nakagawa H, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Okura H, Saito Y.
Value of Placental Growth Factor as a Predictor of Adverse Events During the Acute Phase of Acute Decompensated Heart Failure.
Circ J. 2018 Dec 26.
8. Nakano T, Onoue K, Nakada Y, Nakagawa H, Kumazawa T, Ueda T, Nishida T, Soeda T, Okayama S, Watanabe M, Kawata H, Kawakami R, Horii M, Okura H, Uemura S, Hatakeyama K, Sakaguchi Y, Saito Y.
Alteration of β-Adrenoceptor Signaling in Left Ventricle of Acute Phase Takotsubo Syndrome: a Human Study.
Sci Rep. 2018 Aug 24;8(1):12731.
9. Nishimoto M, Matsui M, Tsushima H, Tanabe K, Tagawa M, Samejima KI, Akai Y, Saito Y.
Acute kidney injury in a postpartum woman with paroxysmal nocturnal hemoglobinuria: A case report and literature review.
Hemodial Int. 2018 Jan;22(1):
10. Okada S, Morimoto T, Ogawa H, Sakuma M, Matsumoto C, Soejima H, Nakayama M, Doi N, Jinnouchi H, Waki M, Masuda I, Saito Y; JPAD Trial Investigators.
Effect of Aspirin on Cancer Chemoprevention in Japanese Patients With Type 2 Diabetes: 10-Year Observational Follow-up of a Randomized Controlled Trial.
Diabetes Care. 2018 Aug;41(8):1757-1764.
11. Okura H, Saito Y, Soeda T, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Nishimura K, Miyamoto Y, Ishihara M; J-MINUET investigators.
Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction:results from J-MINUET.
Heart Vessels. 2018 Nov 2
12. Onishi R, Kanaoka K, Sugiura J, Tokunaga M, Takemoto Y, Onoue K, Yamamoto Y, Horii M, Saito Y.
A Cardiac Variant of Fabry Disease Diagnosed with Chance Urinary Mulberry Cells.
Intern Med. 2018 Jul 6 .1177-18
13. Onoue K, Saito Y.
Hepatitis C Virus and Cardiovascular Disease.
Circ J. 2018 May 8
14. Sakagami A, Okura H, Uemura T, Saito Y.
Inter-atrial Septal Thrombus without PFO.
Intern Med. 2018 Feb 1;57(3):445.
15. Soejima H, Ogawa H, Morimoto T, Okada S, Sakuma M, Nakayama M, Masuda I, Doi N, Uemura S, Jinnouchi H, Sugiyama S, Waki M, Saito Y; JPAD Trial Investigators.
One quarter of total myocardial infarctions are silent manifestation in patients with type 2 diabetes mellitus.
J Cardiol. 2019 Jan;73(1):33-37.
17. Sugiura J, Watanabe M, Toyokawa N, Kamon D, Isojima T, Ueda T, Soeda T, Okura H, Saito Y.
Progression of a Calcified Nodule Causing Acute Myocardial Infarction in a Patient on Hemodialysis - Serial Optical Coherence Tomography.
Circ J. 2018 Aug 24.
20. Takemura G, Onoue K, Nakano T, Nakamura T, Sakaguchi Y, Tsujimoto A, Miyazaki N, Watanabe T, Kanamori H, Okada H, Kawasaki M, Fujiwara T, Fujiwara H, Saito Y.
Possible mechanism for disposal of degenerative cardiomyocytes in human failing hearts: phagocytosis by a neighbour.
ESC Heart Fail. 2018 Nov 27.
21. Toyokawa N, Okura H, Saito Y.
From Mitral Annular Calcification to Calcified Amorphous Tumor.
Intern Med. 2018 Feb 1;57(3):443.
22. Watanabe, M, Okura, H, Okamura, A. Iwai, A, Keshi, A, Kamon, D, Isojima, T, Ueda, T, Soeda, T. Saito, Y.
Usefulness of longitudinal reconstructed optical coherence tomography images for predicting the need for the reverse wire technique during coronary bifurcation interventions.
Catheterization and Cardiovascular Interventions. 2018 Nov 25.

 

共同研究(2018年)

1. Araki M, Hisamitsu T, Kinugasa-Katayama Y, Tanaka T, Harada Y, Nakao S, Hanada S, Ishii S, Fujita M, Kawamura T, Saito Y, Nishiyama K, Watanabe Y, Nakagawa O.
Serum/glucocorticoid-regulated kinase 1 as a novel transcriptional target of bone morphogenetic protein-ALK1 receptor signaling in vascular endothelial cells.
Angiogenesis. 2018 May;21(2):415-423.
2. Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Ohshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET investigators.
A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy.
Heart Vessels. 2018 May;33(5):481-488
3. Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Oshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET investigators.
Pre-Procedural Thrombolysis in Myocardial Infarction Flow in Patients with ST-Segment Elevation Myocardial Infarction.
Int Heart J. 2018 Aug 29.
4. Horiuchi Y, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Yasuda S, Noguchi T, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Shibata Y, Nakai M, Nishimura K, Miyamoto Y,
A High Level of Blood Urea Nitrogen Is a Significant Predictor for In-hospital Mortality in Patients with Acute Myocardial Infarction.
Ishihara M; J-MINUET investigators.
Int Heart J. 2018 Mar 30;59(2):263-271.
5. Itoh H, Komuro I, Takeuchi M, Akasaka T, Daida H, Egashira Y, Fujita H, Higaki J, Hirata KI, Ishibashi S, Isshiki T, Ito S, Kashiwagi A, Kato S, Kitagawa K, Kitakaze M, Kitazono T, Kurabayashi M, Miyauchi K, Murakami T, Murohara T, Node K, Ogawa S, Saito Y, Seino Y, Shigeeda T, Shindo S, Sugawara M, Sugiyama S, Terauchi Y, Tsutsui H, Ueshima K, Utsunomiya K, Yamagishi M, Yamazaki T, Yo S, Yokote K, Yoshida K, Yoshimura M, Yoshimura N, Nakao K, Nagai R; EMPATHY Investigators.
Intensive Treat-to-Target Statin Therapy in High-Risk Japanese Patients With Hypercholesterolemia and Diabetic Retinopathy: Report of a Randomized Study.
Diabetes Care. 2018 Apr 6
7. Nakajima K, Aiba T, Makiyama T, Nishiuchi S, Ohno S, Kato K, Yamamoto Y, Doi T, Shizuta S, Onoue K, Yagihara N, Ishikawa T, Watanabe I, Kawakami H, Oginosawa Y, Murakoshi N, Nogami A, Aonuma K, Saito Y, Kimura T, Yasuda S, Makita N, Shimizu W, Horie M, Kusano K.
Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry.
Circ J. 2018 Aug 4.
8. Solomon SD, Rizkala AR, Lefkowitz MP, Shi VC, Gong J, Anavekar N, Anker SD, Arango JL, Arenas JL, Atar D, Ben-Gal T, Boytsov SA, Chen CH, Chopra VK, Cleland J, Comin-Colet J, Duengen HD, Echeverría Correa LE, Filippatos G, Flammer AJ, Galinier M, Godoy A, Goncalvesova E, Janssens S, Katova T, Køber L, Lelonek M, Linssen G, Lund LH, O'Meara E, Merkely B, Milicic D, Oh BH, Perrone SV, Ranjith N, Saito Y, Saraiva JF, Shah S, Seferovic PM, Senni M, Sibulo AS Jr, Sim D, Sweitzer NK, Taurio J, Vinereanu D, Vrtovec B, Widimský J Jr, Yilmaz MB, Zhou J, Zweiker R, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, McMurray JJV.
Baseline Characteristics of Patients With Heart Failure and Preserved Ejection Fraction in the PARAGON-HF Trial.
Circ Heart Fail. 2018 Jul;11(7) :e004962
9. Takami T, Okada S, Saito Y, Nishijima Y, Kobori H, Nishiyama A.
Effects of Olmesartan and Azilsartan on Albuminuria and the Intrarenal Renin-Angiotensin System.
World J Res Rev. 2018 Jan;6(1):7-10.
10. Tauscher S, Nakagawa H, Völker K, Werner F, Krebes L, Potapenko T, Doose S, Birkenfeld AL, Baba HA, Kuhn M.
β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice.
Cardiovasc Diabetol. 2018 Jul 17;17(1):103
11. Tobita T, Nomura S, Fujita T, Morita H, Asano Y, Onoue K, Ito M, Imai Y, Suzuki A, Ko T, Satoh M, Fujita K, Naito AT, Furutani Y, Toko H, Harada M, Amiya E, Hatano M, Takimoto E, Shiga T, Nakanishi T, Sakata Y, Ono M, Saito Y, Takashima S, Hagiwara N, Aburatani H, Komuro I.
Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling.
Sci Rep. 2018 Jan 31;8(1)
12. Tsutsui H, Momomura SI, Saito Y, Ito H, Yamamoto K, Ohishi T, Okino N, Kitamura T, Guo W.
Angiotensin Receptor Neprilysin Inhibitor in Japanese Patients With Heart Failure and Reduced Ejection Fraction - Baseline Characteristics and Treatment of PARALLEL-HF Trial.
Circ J. 2018 Jul 26. CJ-17-1424. [Epub ahead of print]

原著(2017年)

1. Matsui M, Akai Y, Samejima KI, Tsushima H, Tanabe K, Morimoto K, Tagawa M, Saito Y.
Prognostic Value of Predialysis Indices for Technique Failure and Mortality in Peritoneal Dialysis Patients.
Ther Apher Dial. 2017 Oct;21(5):493-499. doi: 10.1111/1744-9987.12546. Epub 2017 May 15.
2. Toyokawa N, Okura H, Saito Y.
From Mitral Annular Calcification to Calcified Amorphous Tumor.
Intern Med. 2017 Nov 1. doi: 10.2169/internalmedicine.9310-17
3. Sakagami A, Okura H, Uemura T, Saito Y.
Inter-atrial Septal Thrombus without PFO.
Intern Med. 2017 Oct 16. doi: 10.2169/internalmedicine.9308-17. [Epub ahead of print]
4. Nishimoto M, Matsui M, Tsushima H, Tanabe K, Tagawa M, Samejima KI, Akai Y, Saito Y.
Acute kidney injury in a postpartum woman with paroxysmal nocturnal hemoglobinuria: A case report and literature review.
Hemodial Int. 2017 Aug 10. doi: 10.1111/hdi.12591. [Epub ahead of print]
5. Nogi M, Okura H, Sakagami A, Tamaki H, Saito Y.
Progressive mitral regurgitation in a patient with tropical endomyocardial fibrosis.
Eur Heart J Cardiovasc Imaging. 18:1071, 2017
7. Nakada Y, Kawakami R, Matsui M, Ueda T, Nakano T, Takitsume A, Nakagawa N, Nishida T, Onoue K, Soeda T, Okayama S, Watanabe M, Kawata H, Okura H, Saito Y.
Prognostic Value of Urinary Neutrophil Gelatinase-Associated Lipocalin on the First Day of Admission for Adverse Events in Patients with Acute Decompensated Heart Failure.
J Am Heart Assoc. 2017 May 18;6(5). pii: e004582.
8. Morimoto K, Akai Y, Matsui M, Yano H, Tagawa M, Samejima K, Saito Y.
Acute pulmonary thromboembolism occurring during treatment with tolvaptan in a patient with autosomal-dominant polycystic kidney disease.
CEN Case Reports. 6:61-65, 2017.
10. Tagawa M, Ghosn M, Wachtel H, Fraker D, Townsend RR, Trerotola S, Cohen DL.
Lateralization index but not contralateral suppression at adrenal vein sampling predicts improvement in blood pressure after adrenalectomy for primary aldosteronism.
J Hum Hypertens. 31:444-449, 2017
11. Saito Y, Okada S, Ogawa H, Soejima H, Sakuma M, Nakayama M, Doi N, Jinnouchi H, Waki M, Masuda I, Morimoto T; JPAD Trial Investigators.
Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Patients with Type 2 Diabetes: 10-year Follow-up of a Randomized Controlled Trial.
Circulation. 135:659-670, 2017.
12. Kojima S, Matsui K, Ogawa H, Jinnouchi H, Hiramitsu S, Hayashi T, Yokota N, Kawai N, Tokutake E, Uchiyama K, Sugawara M, Kakuda H, Wakasa Y, Mori H, Hisatome I, Waki M, Ohya Y, Kimura K, Saito Y; Febuxostat for Cerebral and Cardiorenovascular Events Prevention Study (FREED) investigators.
Rationale, design, and baseline characteristics of a study to evaluate the effect of febuxostat in preventing cerebral, cardiovascular, and renal events in patients with hyperuricemia.
J Cardiol. 69:169-175, 2017.

共同研究(2017年)

1. Nishiuchi S, Makiyama T, Aiba T, Nakajima K, Hirose S, Kohjitani H, Yamamoto Y, Harita T, Hayano M, Wuriyanghai Y, Chen J, Sasaki K, Yagihara N, Ishikawa T, Onoue K, Murakoshi N, Watanabe I, Ohkubo K, Watanabe H, Ohno S, Doi T, Shizuta S, Minamino T, Saito Y, Oginosawa Y, Nogami A, Aonuma K, Kusano K, Makita N, Shimizu W, Horie M, Kimura T.
Gene-Based Risk Stratification for Cardiac Disorders in Mutation Carriers.
Circ Cardiovasc Genet. 2017 Dec;10(6). doi: 10.1161/CIRCGENETICS.116.001603.
2. Masuda H, Kobayashi T, Hachiya A, Nakashima Y, Shimizu H, Nozawa T, Ogihara Y, Ito S, Takatsuki S, Katsumata N, Suzuki Y, Takenaka S, Hirono K, Kobayashi T, Suzuki H, Suganuma E, Takahashi K, Saji T; Committee of Survey on Infliximab use for Kawasaki disease.
Infliximab for the Treatmen of Refractory Kawasaki Disease: A Nationwide Survey in Japan.
J Pediatr. 2017 Dec 7. doi: 10.1016/j.jpeds.2017.10.013. [Epub ahead of print]
3. Kakizaki Y, Makino N, Ando Y, Matsuda A, Ishizawa T, Saito Y, Suto A, Yamakawa M, Kimura W, Ueno Y.
A case of pancreatic intraepithelial neoplasia-3 with autoimmune pancreatitis.
Nihon Shokakibyo Gakkai Zasshi. 2017;114(6):1023-1030. doi: 10.11405/nisshoshi.114.1023. Japanese.
4. Ito M, Makino N, Matsuda A, Ikeda Y, Kakizaki Y, Saito Y, Ueno Y, Kawata S.
High Glucose Accelerates Cell Proliferation and Increases the Secretion and mRNA Expression of Osteopontin in Human Pancreatic Duct Epithelial Cells.
Int J Mol Sci. 2017 Apr 12;18(4). 10.3390/ijms18040807.
5. Ishihara M, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Fujino M, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Tobaru T, Oshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H; J-MINUET Investigators.
Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation The J-MINUET Study.
Circ J. 2017 Jun 23;81(7):958-965. doi: 10.1253/circj.CJ-17-0033. Epub 2017 Mar 17.
6. Kuji S, Kosuge M, Kimura K, Nakao K, Ozaki Y, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Nishimura K, Miyamoto Y, Ishihara M; J-MINUET Investigators.
Impact of Acute Kidney Injury on In-Hospital Outcomes of Patients With Acute Myocardial Infarction Results From the Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) Substudy.
Circ J. 2017 Apr 25;81(5):733-739. doi: 10.1253/circj.CJ-16-1094. Epub 2017 Feb 9.
7. Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK.
Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study.
J Am Heart Assoc. 2017 Nov 1;6(11). pii: e006241.
8. Bryniarski KL, Walters DL, Kim CJ, Soeda T, Higuma T, Yamamoto E, Xing L, Sugiyama T, Zanchin T, Bryniarski L, Dudek D, Lee H, Jang IK.
SYNTAX Score and Pre- and Poststent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients With Stable Angina Pectoris.
Am J Cardiol. 120:898-903, 2017.
9. Hirai N, Kasahara K, Uno K, Ogawa Y, Ogawa T, Yonekawa S, Nakano R, Yano H, Sakagami A, Uemura T, Okura H, Saito Y, Yoshikawa M, Mikasa K.
Infective Endocarditis Complicated by Intraventricular Abscesses, Pericarditis, and Mycotic Aneurysm Due to an Emerging Strain of Serotype VI Streptococcus agalactiae.
Jpn J Infect Dis. 70:685-686, 2017
10. Fujikura H, Kasahara K, Ogawa Y, Hirai N, Yoshii S, Yoshihara S, Ogawa T, Yonekawa S, Imakita N, Nishioka Y, Yoneda T, Yoshida K, Samejima KI, Tanabe K, Saito Y, Yano H, Mikasa K.
Mycobacterium wolinskyi Peritonitis after Peritoneal Catheter Embedment Surgery.
Intern Med.56:3097-3101, 2017
11. Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Ohshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET investigators.
A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy.
Heart Vessels. 2017 Nov 16. doi: 10.1007/s00380-017-1084-2. [Epub ahead of print]
12. Takahashi N, Saeki T, Komatsuda A, Munemura C, Fukui T, Imai N, Homma N, Hatta T, Samejima KI, Fujimoto T, Omori H, Ito Y, Nishikawa Y, Kobayashi M, Morikawa Y, Fukushima S, Yokoi S, Mikami D, Kasuno K, Kimura H, Nemoto T, Nakamoto Y, Sada K, Sugai M, Naiki H, Yoshida H, Narita I, Saito Y, Iwano M.
Tubulointerstitial Nephritis with IgM-Positive Plasma Cells.
J Am Soc Nephrol. 2017 Aug 9. pii: ASN.2016101074. doi: 10.1681/ASN.2016101074. [Epub ahead of print]
13. Ogita M, Suwa S, Ebina H, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Hokimoto S, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Oshima S, Nishimura K, Miyamoto Y, Ishihara M; J-MINUET investigators.
Off-hours presentation does not affect in-hospital mortality of Japanese patients with acute myocardial infarction: J-MINUET substudy.
J Cardiol. 2017 Jul 3. pii: S0914-5087(17)30158-2. doi: 10.1016/j.jjcc.2017.05.006. [Epub ahead of print]
14. Momomura SI, Saito Y, Yasumura Y, Yamamoto K, Sakata Y, Daimon M, Kinugawa K, Okamoto H, Dohi N, Komuro I.
Efficacy and Safety of Switching From Oral Bisoprolol to Transdermal Patch in Japanese Patients With Chronic Heart Failure.
Circ J. 2017 Aug 2. doi: 10.1253/circj.CJ-17-0532. [Epub ahead of print]
15. Kobayashi Y, Okura H, Kobayashi Y, Fukuda S, Hirohata A, Yoshida K.
Left ventricular myocardial function assessed by three-dimensional speckle tracking echocardiography in Takotsubo cardiomyopathy.
Echocardiography. 34:523-529, 2017.
16. Hu S, Zhu Y, Zhang Y, Dai J, Li L, Dauerman H, Soeda T, Wang Z, Lee H, Wang C, Zhe C, Wang Y, Zheng G, Zhang S, Jia H, Yu B, Jang IK.
Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study.
J Am Heart Assoc. 2017 Feb 24;6(3). pii: e004730.
18. Kume T, Okura H, Yamada R, Koyama T, Fukuhara K, Goryo Y, Kamata Y, Okamoto H, Tamada T, Imai K, Neishi Y, Uemura S.
In vivo assessment of vasa vasorum neovascularization using intravascular ultrasound: A comparison between acute coronary syndrome and stable angina pectoris.
J Cardiol. 69:601-605, 2017
19. Dai J, Hou J, Xing L, Jia H, Hu S, Soeda T, Minami Y, Ong D, Vergallo R, Zhang S, Lee H, Yu B, Jang IK.
Is age an important factor for vascular response to statin therapy? A serial optical coherence tomography and intravascular ultrasound study.
Coron Artery Dis. 28:209-217, 2017
20. Sato A, Aonuma K, Watanabe M, Hirayama A, Tamaki N, Tsutsui H, Toyoaki M, Ogawa H, Akasaka T, Yoshimura M, Takayama T, Sakakibara M, Suzuki S, Ishigami K, Onoue K, Saito Y; CINC-J study investigators.
Association of contrast-induced nephropathy with risk of adverse clinical outcomes in patients with cardiac catheterization: From the CINC-J study.
Int J Cardiol. 227: 424-429, 2017.
21. Kobayashi Y, Okura H, Neishi Y, Higa T, Kobayashi Y, Uemura S, Yoshida K.
Additive value of nicorandil on ATP for further inducing hyperemia in patients with an intermediate coronary artery stenosis.
Coron Artery Dis. 28:104-109, 2017

原著(2016年)

1. Matsui M, Samejima K, Takeda Y, Morimoto K, Tagawa M, Onoue K, Okayama S, Kawata H, Kawakami R, Akai Y, Okura H, Saito Y.
Angiogenic Factors and Risks of Technique Failure and Cardiovascular Events in Patients Receiving Peritoneal Dialysis.
Cardiorenal Med. 6: 251-259, 2016.
2. Nakada Y, Kawakami R, Nakano T, Takitsume A, Nakagawa H, Ueda T, Nishida T, Onoue K, Soeda T, Okayama S, Takeda Y, Watanabe Y, Kawata H, Okura H, Saito Y.
Gender Differences in Clinical Characteristics and Long-Term Outcome in Acute Decompensated Heart Failure Patients with Preserved and Reduced Ejection Fraction
Am J Physiol Heart Circ Physiol. 310:H813-820, 2016
3. Nakagawa H, Mizuno Y, Harada E, Morikawa Y, Kuwahara K, Saito Y, Yasue H.
Brain Natriuretic Peptide Counteracting the Renin-angiotensin-aldosterone System in Accelerated Malignant Hypertension.
Am J Med Sci. 352:534-539, 2016.
4. Nakagawa H, Somekawa S, Onoue K, Kumazawa T, Ueda T, Seno A, Nakada Y, Nakano T, Matsui M, Soeda T, Okayama S, Kawakami R, Kawata H, Okura H, Saito Y.
Salt accelerates aldosterone-induced cardiac remodeling in the absence of guanylyl cyclase-A signaling.
Life Sci. 165:9-15, 2016.
5. Okada S, Morimoto T, Ogawa H, Sakuma M, Soejima H, Nakayama M, Jinnouchi H, Waki M, Akai Y, Ishii H, Saito Y; investigators for the Japanese Primary Prevention of Atherosclerosis with Aspirin for Diabetes (JPAD) trial.
Is Long-Term Low-Dose Aspirin Therapy Associated with Renal Dysfunction in Patients with Type 2 Diabetes? JPAD2 Cohort Study.
PLoS One. 11;e0147635, 2016.
6. Seno A, Takeda Y, Matsui M, Okuda A, Nakano T, Yasuki N, Kumasawa T, Hitoshi N, Nishida T, Onoue K, Somekawa S, Watanabe M, Kawata H, Kawakami R, Okura H, Uemura S, Saito Y.
Suppressed Production of Soluble Fms-like Tyrosine Kinase-1 Contributes to Myocardial Remodeling and Heart Failure
Hypertension. 68: 678-87, 2016.
7. Soeda T, Higuma T, Abe N, Yamada M, Yokoyama H, Shibutani S, Ong DS, Vergallo R, Minami Y, Lee H, Okumura K, Jang IK.
Morphological predictors for no reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction caused by plaque rupture.
Eur Heart J Cardiovasc Imaging. 27:435-6, 2016.
8. Soeda T, Uemura S, Watanabe M, Ishihara S, Ueda T, Sugawara Y, Okura H, Saito Y.
Multifocal coronary thrombosis on nondisrupted plaque: observation with optical coherence tomography.
Coron Artery Dis. 27:435-436, 2016.
9. Takemura G, Onoue K, Kashimura T, Kanamori H, Okada H, Tsujimoto A, Miyazaki N, Nakano T, Sakaguchi Y, Saito Y.
Electron Microscopic Findings Are an Important Aid for Diagnosing Mitochondrial Cardiomyopathy With Mitochondrial DNA Mutation 3243A>G.
Circ Heart Fail. 2016 Jul;9(7). pii: e003283.
10. Ueda T, Uemura S, Watanabe M, Dote Y, Goryo Y, Sugawara Y, Soeda T, Okayama S, Kawata H, Kawakami R, Okura H, Saito Y.
Thin-cap fibroatheroma and large calcification at the proximal stent edge correlate with a high proportion of uncovered stent struts in the chronic phase.
Coron Artery Dis. 27:376-84, 2016
11. Watanabe M, Uemura S, Kita Y, Sugawara Y, Goryo Y, Ueda T, Soeda T, Okayama S, Okura H, Kume T, Saito Y.
Impact of branching angle on neointimal coverage of drug-eluting stents implanted in bifurcation lesions
Coron Artery Dis. 27:682-689, 2016

共同研究(2016年)

1. Sato A, Aonuma K, Watanabe M, Hirayama A, Tamaki N, Tsutsui H, Toyoaki M, Ogawa H, Akasaka T, Yoshimura M, Takayama T, Sakakibara M, Suzuki S, Ishigami K, Onoue K, Saito Y; CINC-J study investigators.
Association of contrast-induced nephropathy with risk of adverse clinical outcomes in patients with cardiac catheterization: From the CINC-J study.
Int J Cardiol. 2017 Jan 15;227:424-429. doi: 10.1016/j.ijcard.2016.11.019. Epub 2016 Nov 7.
2. Tsutsui H, Momomura S, Yamashina A, Ogawa H, Shimokawa H, Kihara Y, Saito Y, Hagiwara N, Ito H, Ako J, Inomata T, Tanaka T, Kawasaki Y; study investigators.
Heart Rate Control With If Inhibitor, Ivabradine, in Japanese Patients With Chronic Heart Failure A Randomized, Double-Blind, Placebo-Controlled Phase II Study.
Circ J. 2016;80(3):668-76. doi: 10.1253/circj.CJ-15-1112. Epub 2016 Jan 14.
3. Sakamoto T, Ogawa H, Nakao K, Hokimoto S, Tsujita K, Koide S, Yamamoto N, Shimomura H, Matsumura T, Oshima S, Kikuta K, Oka H, Kimura K, Matsui K; 4C (Candesartan for Prevention of Cardiovascular Events after CYPHER? or TAXUS? Coronary Stenting) study investigators.
Impact of candesartan on cardiovascular events after drug-eluting stent implantation in patients with coronary artery disease: The
J Cardiol. 2016 Apr;67(4):371-7. doi: 10.1016/j.jjcc.2015.06.009. Epub 2015 Aug 4.
4. Bryniarski KL, Tahk SJ, Choi SY, Soeda T, Higuma T, Yamamoto E, Xing L, Dai J, Zanchin T, Lee H, Jang IK.
Clinical, Angiographic, IVUS, and OCT predictors for Irregular Protrusion after coronary stenting.
EuroIntervention. 2016 Dec 20. pii: EIJ-D-16-00679. doi: 10.4244/EIJ-D-16-00679. [Epub ahead of print]
5. Fujino M, Ishihara M, Ogawa H, Nakao K, Yasuda S, Noguchi T, Ozaki Y, Kimura K, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Ako J, Nakai M, Nishimura K, Miyamoto Y; J-MINUET Investigators.
Impact of symptom presentation on in-hospital outcomes in patients with acute myocardial infarction.
J Cardiol. 2016 Nov 14. pii: S0914-5087(16)30240-4.
6. Fukuhara K, Okura H, Kume T, Yamada R, Neishi Y, Uemura S.
In-stent neointimal characteristics and late neointimal response after drug-eluting stent implantation: A preliminary observation.
J Cardiol. 67:437-41, 2016
7. Gao L, Lee S, Kim CJ, Minami Y, Ong DS, Soeda T, Lowe H, Choi SY, Lerman A, Lee J, Lee H, Uemura S, Yu B, Jang IK.
Incidence and Morphological Predictors of Intrastent Coronary Thrombus After Drug-Eluting Stent Implantation (from a Multicenter Registry).
Am J Cardiol. 117:369-75, 2016
8. Gin AL, Vergallo R, Minami Y, Ong DS, Hou J, Jia H, Soeda T, Hu S, Zhang S, Lee H, Yu B, Jang IK.
Changes in coronary plaque morphology in patients with acute coronary syndrome versus stable angina pectoris after initiation of statin therapy.
Coron Artery Dis. 2016 Jul 27. [Epub ahead of print]
9. Gin AL, Vergallo R, Minami Y, Ong DS, Hou J, Jia H, Soeda T, Hu S, Zhang S, Lee H, Yu B, Jang IK.
Changes in coronary plaque morphology in patients with acute coronary syndrome versus stable angina pectoris after initiation of statin therapy.
Coron Artery Dis. 27:629-635, 2016.
10. Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Izumiyama K, Nishizaki F, Minami Y, Xing L, Yamamoto E, Lee H, Okumura K, Jang IK.
Does Residual Thrombus After Aspiration Thrombectomy Affect the Outcome of Primary PCI in Patients With ST-Segment Elevation Myocardial Infarction?: An Optical Coherence Tomography Study.
JACC Cardiovasc Interv.9: 2002-2011, 2016
11. Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Nishizaki F, Xing L, Yamamoto E, Bryniarski K, Dai J, Lee H, Okumura K, Jang IK.
Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment-Elevation Myocardial Infarction: A Combined Optical Coherence Tomography and Intravascular Ultrasound Study.
Circ Cardiovasc Interv. 9: pii: e003913, 2016
12. Hou J, Xing L, Jia H, Vergallo R, Soeda T, Minami Y, Hu S, Yang S, Zhang S, Lee H, Yu B, Jang IK.
Comparison of Intensive Versus Moderate Lipid-Lowering Therapy on Fibrous Cap and Atheroma Volume of Coronary Lipid-Rich Plaque Using Serial Optical Coherence Tomography and Intravascular Ultrasound Imaging.
Am J Cardiol. 2015 Dec 13. pii: S0002-9149(15)02352-8.
13. Kagiyama N, Okura H, Matsue Y, Tamada T, Imai K, Yamada R, Kume T, Hayashida A, Neishi Y, Yoshida K.
Multiple Unfavorable Echocardiographic Findings in Takotsubo Cardiomyopathy Are Associated with Increased In-Hospital Events and Mortality.
J Am Soc Echocardiogr. 2016 Oct 11. pii: S0894-7317(16)30430-8
14. Kagiyama N, Okura H, Tamada T, Imai K, Yamada R, Kume T, Hayashida A, Neishi Y, Kawamoto T, Yoshida K.
Impact of right ventricular involvement on the prognosis of takotsubo cardiomyopathy.
Eur Heart J Cardiovasc Imaging. 17:210-6, 2016
15. Kume T, Okura H, Yamada R, Koyama T, Fukuhara K, Goryo Y, Kamata Y, Okamoto H, Tamada T, Imai K, Neishi Y, Uemura S.
In vivo assessment of vasa vasorum neovascularization using intravascular ultrasound: A comparison between acute coronary syndrome and stable angina pectoris.
J Cardiol. 2016 Oct 25. pii: S0914-5087(16)30222-2.
16. Kimura Y, Tanaka N, Okura H, Yoshida K, Akabane M, Takayama T, Hirayama A, Tada T, Kimura T, Takano H, Mizuno K, Inami T, Yoshino H, Yamashina A.
Characterization of real-world patients with low fractional flow reserve immediately after drug-eluting stents implantation.
Cardiovasc Interv Ther. 31:29-37, 2016
17. Kume T, Okura H, Yamada R, Koyama T, Fukuhara K, Kawamura A, Imai K, Neishi Y, Uemura S.
Detection of Plaque Neovascularization by Optical Coherence Tomography: Ex Vivo Feasibility Study and In Vivo Observation in Patients With Angina Pectoris.
J Invasive Cardiol. 28:17-22, 2016
18. Kume T, Okura H, Yamada R, Koyama T, Fukuhara K, Goryo Y, Kamata Y, Okamoto H, Tamada T, Imai K, Neishi Y, Uemura S.
In vivo assessment of vasa vasorum neovascularization using intravascular ultrasound: A comparison between acute coronary syndrome and stable angina pectoris.
J Cardiol. 2016 Oct 25. pii: S0914-5087(16)30222-2. doi: 10.1016/j.jjcc.2016.09.013. [Epub ahead of print]

原著(2015年)

1. Kumazawa T, Nishimura K, Katagiri N, Hashimoto S, Hayashi Y, Kimura K.
Gradual reduction in rRNA transcription triggers p53 acetylation and apoptosis via MYBBP1A.
Sci Rep. 5:10854, 2015.
2. Kurokawa M, Uemura S, Watanabe M, Dote Y, Sugawara Y, Goryo Y, Ueda T, Okayama S, Kayashima M, Saito Y.
Changes in the reference lumen size of target lesions before and after coronary stent implantation: Evaluation with frequency domain optical coherence tomography.
Int J Cardiol Heart Vasc. 2015 Jun 17;8:122-127. doi: 10.1016/j.ijcha.2015.06.003. eCollection 2015 Sep 1.
3. Matsui M, Samejima K, Takeda Y, Tanabe K, Morimoto K, Okamoto K, Tagawa M, Onoue K, Okayama S, Kawata H, Kawakami R, Akai Y, Saito Y.
Prognostic Impact of Placental Growth Factor on Mortality and Cardiovascular Events in Dialysis Patients.
Am J Nephrol. 42: 117-125, 2015.
4. Matsui M, Uemura S, Takeda Y, Samejima K, Matsumoto T, Hasegawa A Tsushima H, Hoshino E, Ueda T, Morimoto K, Okamoto K, Okada S, Onoue K, Okayama S, Kawata H, Kawakami R, Maruyama N, Akai Y, Iwano M, Shiiki H, Saito Y, for the NARA-CKD investigators.
Placental Growth Factor As A Predictor Of Cardiovascular Events In Patients With Chronic Kidney Disease from the Novel Assessment of Risk management for Atherosclerotic diseases in Chronic Kidney Disease (NARA-CKD) Study.
J Am Soc Nephrol. 26:2871-81, 2015.
5. Mizuno R, Yamagami S, Higashi T, Nakada Y, Takeda Y, Okayama S, Fujimoto S, Saito Y.
Major noncardiac surgery is a risk factor for rapid hemodynamic progression of non-rheumatic aortic stenosis.
Circ J.79:867-72,2015.
6. Nakada Y, Okayama S, Nakano T, Ueda T, Takeda Y, Kawakami R, Horii M, Uemura S, Fujimoto S, Saito Y.
Echocardiographic characteristics of patients with acute heart failure requiring tolvaptan: a retrospective study.
Cardiovascular Ultrasound. 13:27, 2015.
7. Neishi Y, Okura H, Kume T, Fukuhara K, Yamada R, Yoshida K.
Prediction of chronic vessel enlargement by a novel intravascular ultrasound finding.
Circ J. 79:607-12, 2015.
8. Okayama S, Soeda T, Kawakami R, Takami Y, Somekawa S, Ueda T, Sugawara Y, Matsumoto T, Sung JH, Nishida T, Uemura S, Saito Y.
Evaluation of coronary artery disease and cardiac morphology and function in patients with hypertrophic cardiomyopathy, using cardiac computed tomography.
Heart Vessels. 30:28-35,2015.
9. Saito Y, Watanabe M, Aonuma K, Hirayama A, Tamaki N, Tsutsui H, Murohara T, Ogawa H, Akasaka T, Yoshimura M, Sato A, Takayama T, Sakakibara M, Suzuki S, Ishigami K, Onoue K; CINC-J study investigators.
Proteinuria and Reduced Estimated Glomerular Filtration Rate Are Independent Risk Factors for Contrast-Induced Nephropathy After Cardiac Catheterization.
Circ J. 79:1624-30, 2015.
10. Soeda T, Uemura S, Park SJ, Jang Y, Lee S, Cho JM, Kim SJ, Vergallo R, Minami Y, Ong DS, Gao L, Lee H, Zhang S, Yu B, Saito Y, Jang IK.
Incidence and Clinical Significance of Post-Stent OCT Findings: One Year Follow-Up Study From a Multicenter Registry.
Circulation. 132: 1020-9, 2015.
12. Ueda T, Kawakami R, Nishida T, Onoue K, Soeda T, Okayama S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
Left Ventricular Ejection Fraction (EF) of 55% as Cutoff for Late Transition From Heart Failure (HF) With Preserved EF to HF With Mildly Reduced EF.
Circ J. 79: 2209-15, 2015.
13. Ueda T, Kawakami R, Nishida T, Onoue K, Soeda T, Okayama S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
Plasma Renin Activity Is a Strong and Independent Prognostic Indicator in Patients With Acute Decompensated Heart Failure Treated With Renin-Angiotensin System Inhibitors.
Circ J. 79:1307-14, 2015.
14. Watanabe M, Saito Y, Aonuma K, Hirayama A, Tamaki N, Tsutsui H, Murohara T, Ogawa H, Akasaka T, Yoshimura M, Sato A, Takayama T, Sakakibara M, Suzuki S, Ishigami K, Onoue K; CINC-J study investigators.
Prediction of contrast-induced nephropathy by the serum creatinine level on the day following cardiac catheterization.
J Cardiol. 2015 Dec 18. pii: S0914-5087(15)00358-5.

共同研究(2015年)

1. Asakura M, Yamamoto H, Asai K, Hanatani A, Hirata KI, Hirayakma A, Kimura K, Kobayashi Y, Momomura SI, Nakagawa Y, Nishi Y, Saito Y, Satoh Y, Yamada T, Yamashina A, Yasuda S, Yoshikawa T, Kada A, Uesaka H, Kitakaze M; on behalf of the EARLIER investigators and study coordinators.
Rationale and Design of the Double-Blind, Randomized, Placebo-Controlled Multicenter Trial on Efficacy of Early Initiation of Eplerenone Treatment in Patients with Acute Heart Failure (EARLIER).
Cardiovasc Drugs Ther. 29:179-85, 2015.
2. Fukuhara K, Okura H, Kume T, Yamada R, Neishi Y, Uemura S.
In-stent neointimal characteristics and late neointimal response after drug-eluting stent implantation: A preliminary observation.
J Cardiol. 2015 Aug 11. pii: S0914-5087(15)00208-7.
4. Gao L, Park SJ, Jang Y, Lee S, Kim CJ, Minami Y, Ong D, Soeda T, Vergallo R, Lee H, Yu B, Uemura S, Jang IK.
Comparison of Neoatherosclerosis and Neovascularization Between Patients With and Without Diabetes: An Optical Coherence Tomography Study.
JACC Cardiovasc Interv. 8:1044-52, 2015.
5. Gao L, Park SJ, Jang Y, Lee S, Tian J, Minami Y, Jia H, Ong D, Soeda T, Vergallo R, Lee H, Yu B, Uemura S, Jang IK.
Optical coherence tomographic evaluation of the effect of cigarette smoking on vascular healing after sirolimus-eluting stent implantation.
Am J Cardiol.115:751-7,2015.
7. Imai K, Kawata M, Okura H, Uemura S.
Accessory mitral valve tissue with mitral complex structural abnormality.
J Echocardiogr. 13:76-78, 2015.
8. Imamaki H, Ishii A, Yokoi H, Kasahara M, Kuwabara T, Mori KP, Kato Y, Kuwahara T, Satoh M, Nakatani K, Saito Y, Tomosugi N, Sugawara A, Nakao K, Mukoyama M, Yanagita M, Mori K.
Low Serum Neutrophil Gelatinase-associated Lipocalin Level as a Marker of Malnutrition in Maintenance Hemodialysis Patients.
PLoS One.10: e0132539, 2015.
9. Ishihara M, Fujino M, Ogawa H, Yasuda S, Noguchi T, Nakao K, Ozaki Y, Kimura K, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Tsujita K, Nishimura K, Miyamoto Y; J-MINUET investigators.
Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era - Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET).
Circ J. 79:1643, 2015.
10. Jia H, Hu S, Uemura S, Park SJ, Jang Y, Prasad A, Lee S, Soeda T, Abtahian F, Vergallo R, Tian J, Lee H, Stone PH, Yu B, Jang IK.
Insights into the spatial distribution of lipid-rich plaques in relation to coronary artery bifurcations: an in-vivo optical coherence tomography study.
Coron Artery Dis.26:133-41,2015.
11. Katagiri N, Kuroda T, Kishimoto H, Hayashi Y, Kumazawa T, Kimura K.
The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription.
Sci Rep. 2015 Mar 10;5:8903. doi: 10.1038/srep08903.
12. Kobayashi K, Tanaka T, Okada S, Morimoto Y, Matsumura S, Manio MC, Inoue K, Kimura K, Yagi T, Saito Y, Fushiki T, Inoue H, Matsumoto M, Nabeshima YI.
Hepatocyte β-Klotho regulates lipid homeostasis but not body weight in mice.
FASEB J. 2015 Oct 29.[Epub ahead of print]
13. Kobayashi Y, Okura H, Kume T, Miyamoto Y, Yamada R, Kobayashi Y, Fukuhara K, Koyama T, Neishi Y, Yoshida K.
Direct relationship of local C-reactive protein production and lipid pool characterized by integrated backscatter intravascular ultrasound: a preliminary observation.
Coron Artery Dis. 26, 425-31, 2015.
14. Koyama T, Okura H, Kume T, Fukuhara K, Neishi Y, Hayashida A, Kawamoto T, Yoshida K.
Calcified plaque ablated by rotational atherectomy visualised by optical coherence tomography.
EuroIntervention. 11:e1, 2015.
15. Matsue Y, Kagiyama N, Yoshida K, Kume T, Okura H, Suzuki M, Matsumura A, Yoshida K, Hashimoto Y.
Carperitide Is Associated With Increased In-Hospital Mortality in Acute Heart Failure: A Propensity Score-Matched Analysis.
J Card Fail. 21:859-64, 2015.
16. Minami Y, Ong DS, Uemura S, Wang Z, Aguirre AD, Mukhopadhyay S, Soeda T, Vergallo R, Jia H, Tian J, Hu S, Kim SJ, Park CB, Dauerman HL, Lee S, Jang IK.
Impacts of lesion angle on incidence and distribution of acute vessel wall injuries and strut malapposition after drug-eluting stent implantation assessed by optical coherence tomography.
Eur Heart J Cardiovasc Imaging. 16:1390-8, 2015.
17. Minami Y, Phipps JE, Hoyt T, Milner TE, Ong DS, Soeda T, Vergallo R, Feldman MD, Jang IK.
Clinical utility of quantitative bright spots analysis in patients with acute coronary syndrome: an optical coherence tomography study.
Int J Cardiovasc Imaging. 31: 1479-87, 2015.
18. Mizuta K, Sakabe M, Hashimoto A, Ioka T, Sakai C, Okumura K, Hattammaru M, Fujita M, Araki M, Somekawa S, Saito Y, Nakagawa O.
Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.
Dev Dyn. 244:31-42,2015.
19. Nishimura K, Kumazawa T, Kuroda T, Katagiri N, Tsuchiya M, Goto N, Furumai R, Murayama A, Yanagisawa J, Kimura K.
Perturbation of ribosome biogenesis drives cells into senescence through 5S RNP-mediated p53 activation.
DCell Rep. 10:1310-23,2015.
20. Vergallo R, Aguirre AD, Abtahian F, Minami Y, Soeda T, Chatzizisis YS, Croce K, Jang IK.
Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome.
Thromb Haemost. 2015 Oct 1.[Epub ahead of print]
21. Yamada R, Yoshida K, Okura H.
Progression of cardiac allograft vasculopathy detected by optical coherence tomography.
Coron Artery Dis. 26, 459-60, 2015.

原著(2014年)

1. Horii M, Saito Y.
Author's reply.[Cardiomyopathy: progress in diagnosis and treatments. Topics: III. Diagnosis leading to selection of therapy: 2. Biomarker]
J Cardiol. 2014 Apr 8. pii: S0914-5087(14)00026-4. doi: 10.1016/j.jjcc.2014.01.008. [Epub ahead of print]
2. Matsui M, Takeda Y, Uemura S, Matsumoto T, Seno A, Onoue K, Tsushima H, Morimoto K, Soeda T, Okayama S, Somekawa S, Samejima K, Kawata H, Kawakami R, Nakatani K, Iwano M, Saito Y,
Suppressed Soluble Fms-Like Tyrosine Kinase-1 Production Aggravates Atherosclerosis in CKD : Evaluation by Circulating sFlt-1 Levels after Low-Dose Heparin Injection.
Kidney Int.85:393-403,2014.
3. Matsui M, Okayama S, Tsushima H, Samejima K, Kanki T, Hasegawa A, Morimoto K, Akai Y, Takano M, Uemura S, Ohbayashi C, Saito Y.
Therapeutic Benefits of Tocilizumab Vary in Different Organs of a Patient with AA Amyloidosis.
Case Rep Nephrol. 2014;2014:823093. doi: 10.1155/2014/823093. Epub.
4. Nakagawa H, Oberwinkler H, Nikolaev VO, Gabner B, Umbenauer S, Wagner H, Saito Y, Baba HA, Frantz S, Kuhn M.
Atrial Natriuretic Peptide Locally Counteracts the Deleterious Effects of Cardiomyocyte Mineralocorticoid Receptor Activation.
Circ Heart Fail. 7:814-21, 2014.
5. Nakagawa H, Okayama S, Kamon D, Nakano T, Onoue K, Kawakami R, Horii M, Sakaguchi Y, Uemura S, Takemura G, Saito Y.
Refractory high output heart failure in a patient with primary mitochondrial respiratory chain disease.
Intern Med. 53:315-9, 2014.
6. Okayama S, Tanaka K, Kawata H, Dote Y, Matsui M, Samejima K, Takeda Y, Uemura S, Saito Y
Evaluation of cardiac prognosis in hemodialysis patients by using coronary computed tomography angiography and thallium single photon emission computed tomography: a retrospective study Experimental & Clinical Cardiology in press.
7. Okayama S, Nakada Y, Uemura S, Saito Y.
Three different morphologies of inferior vena cava thrombosis: case reports.
Case Rep Vasc Med. 2014;2014:349213. doi: 10.1155/2014/349213. Epub 2014 Mar 4.
8. Okayama S, Sugimoto M, Nakano T, Onoue K, Sakaguchi Y, Uemura S, Saito Y
Cardiac amyloidosis incidentally detected using technetium-99m hydroxymethylene diphosphonate bone scintigraphy in a patient with prostate cancer IJC Heart & Vessels.
9. Okayama.S, Nakada Y, Uemura S, Saito Y.
Three different morphologies of inferior vena cava thrombosis.
Case Rep in Vasc Med. 2014; 2014: 349213. doi: 10. 1155/ 2014/ 349213. Epub 2014 Mar 4.
10. Onoue K, Nkano T, Saito Y.
Cardiomyopathy: progress in diagnosis and treatments.
Topics: III. Diagnosis leading to selection of therapy: 2. Biomarker Nihon Naika Gakkai Zasshi 103: 345-52, 2014
11. Sakan H, Nakatani K, Asai O, Imura A, Tanaka T, Yoshimoto S, Iwamoto N, Kurumatani N, Iwano M, Nabeshima Y, Konishi N, Saito Y.
Reduced renal α-Klotho expression in CKD patients and its effect on renal phosphate handling and vitamin D metabolism.
PLoS One.9: e86301, 2014.
12. Ueda T, Kawakami R, Sugawara Y, Okada S, Nishida T, Onoue K, Soeda T, Okayama S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
Worsening of renal function during 1 year after hospital discharge is a strong and independent predictor of all-cause mortality in acute decompensated heart failure.
J Am Heart Assoc. 3:e001174,2014.
13. Ueda T, Uemura S, Watanabe M, Sugawara Y, Soeda T, Okayama S, Takeda Y, Kawata H, Kawakami R, Saito Y.
Colocalization of thin-cap fibroatheroma and spotty calcification is a powerful predictor of procedure-related myocardial injury after elective coronary stent implantation.
Coron Artery Dis. 25:384-91, 2014.
14. Ueda T, Kawakami R, Horii M, Sugawara Y, Matsumoto T, Okada S, Nishida T, Soeda T, Okayama S, Somekawa S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y.
Noncardiovascular death, especially infection, is a significant cause of death in elderly patients with acutely decompensated heart failure.
J Card Fail.20:174-80, 2014.
15. Watanabe M, Uemura S, Sugawara Y, Ueda T, Soeda T, Takeda Y, Kawata H, Kawakami R, Saito Y.
Side branch complication after a single-stent crossover technique: prediction with frequency domain optical coherence tomography.
Coron Artery Dis. 25: 321-9, 2014.

共同研究(2014年)

1. Morita S, Mizuno Y, Harada E, Nakagawa H, Morikawa Y, Saito Y, Katoh D, Kashiwagi Y, Yoshimura M, Murohara T, Yasue H.
Differences and interactions between risk factors for coronary spasm and atherosclerosis--smoking, aging, inflammation, and blood pressure.
Intern Med. 2014;53(23):2663-70. Epub 2014 Dec 1.
3. Mizuno R, Fujimoto S, Saito Y, Okamoto Y.
Detection of latent anthracycline-induced cardiotoxicity using left ventricular end-systolic wall stress-velocity of circumferential fiber-shortening relationship.
Heart Vessels. 2014 May;29(3):384-9. doi: 10.1007/s00380-013-0375-5. Epub 2013 Jun 19.
4. Shimamoto K, Ando K, Fujita T, Hasebe N, Higaki J, Horiuchi M, Imai Y, Imaizumi T, Ishimitsu T, Ito M, Ito S, Itoh H, Iwao H, Kai H, Kario K, Kashihara N, Kawano Y, Kim-Mitsuyama S, Kimura G, Kohara K, Komuro I, Kumagai H, Matsuura H, Miura K, Morishita R, Naruse M, Node K, Ohya Y, Rakugi H, Saito I, Saitoh S, Shimada K, Shimosawa T, Suzuki H, Tamura K, Tanahashi N, Tsuchihashi T, Uchiyama M, Ueda S, Umemura S; Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension.
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014).
Hypertens Res. 37:253-387, 2014.
6. Tian J, Dauerman H, Toma C, Samady H, Itoh T, Kuramitsu S, Domei T, Jia H, Vergallo R, Soeda T, Hu S, Minami Y, Lee H, Yu B, Jang IK.
Prevalence and characteristics of TCFA and degree of coronary artery stenosis: an OCT, IVUS, and angiographic study.
J Am Coll Cardiol. 64:672-80, 2014.
7. Vergallo R, Ren X, Yonetsu T, Kato K, Uemura S, Yu B, Jia H, Abtahian F, Aguirre AD, Tian J, Hu S, Soeda T, Lee H, McNulty I, Park SJ, Jang Y, Prasad A, Lee S, Zhang S, Porto I, Biasucci LM, Crea F, Jang IK.
Pancoronary plaque vulnerability in patients with acute coronary syndrome and ruptured culprit plaque: a 3-vessel optical coherence tomography study.
Am Heart J. 167: 59-67, 2014.
8. Wang Z, Jia H, Tian J, Soeda T, Vergallo R, Minami Y, Lee H, Aguirre A, Fujimoto JG, Jang IK.
Computer-aided image analysis algorithm to enhance in vivo diagnosis of plaque erosion by intravascular optical coherence tomography.
Circ Cardiovasc Imaging. 7: 805-10, 2014

原著(2013年 筆頭著者アルファベット順)

1. Morikawa Y, Mizuno Y, Harada E, Katoh D, Kashiwagi Y, Morita S, Yoshimura M, Uemura S, Saito Y, Yasue H
Aerobic interval exercise training in the afternoon reduces attacks of coronary spastic angina in conjunction with improbvement in endothelial function, oxidative stress, and inflammation.
Coron Artery Dis. 24: 177-82, 2013.
2. Horii M, Matsumoto T, Uemura S, Sugawara Y, Takitsume A, Ueda T, Nakagawa H, Nishida T, Soeda T, Okayama S, Somekawa, Ishigami K, Takeda Y, Kawata H, Kawakami R, Saito Y.
Prognostic value of B-type natriuretic peptide (BNP) and its amino-terminal proBNP fragment for cardiovascular events with stratification by renal function.
J Cardiol. 61: 410-6, 2013.
3. Matsui M, Okayama S, Samejima K, Saito Y.
Unforeseen renal pathological findings in a patient with type 2 cardiorenal syndrome who died after four years of continuous ambulatory peritoneal dialysis.
BMJ Case Rep. 2013 Jan 24;2013. doi:pii: bcr2012008103. 10.1136/bcr-2012-008103.
4. Matsumoto T, Uemura S, Takeda Y, Matsui M, Okada S, Nishida T, Soeda T, Okayama S, Somekawa S, Ishigami K, Onoue K, Kawata H, Kawakami R, Horii M, Saito Y
An Elevated Ratio of Placental Growth Factor to Soluble Fms-Like Tyrosine Kinase-1 Predicts Adverse Outcomes in Patients with Stable Coronary Artery Disease.
Intern Med. 52: 1019-27, 2013.
5. Nakatani K, Yoshimoto S, Asai O, Sakan H, Terada M, Saito Y, Nose M, Iwano M, Konishi N
Enhanced expression of the soluble from of E-selectin attenuates progression of lupus nephritis and vasculitis in MRL/lpr mice Immun Inflamm Dis.
2013 Oct;1(1):37-46. doi: 10.1002/iid3.6. Epub.
6. Okada S, Morimoto T, Ogawa H, Sakuma M, Soezima H, Nakayama M, Sugiyama S, Jinnouchi H, Waki M, Doi N, Horii M, Kawata H, Somekawa S, Soeda T, Uemura S, Saito Y
Effect of low-dose aspirin on primary prevention of cardiovascular events in Japanese diabetic patients at high risk.
Circ. J. 2013 Nov 25;77(12):3023-8. Epub 2013 Sep 13.
7. Okayama S, Nakano T, Uemura S, Fujimoto S, Somekawa S, Watanabe M, Nakajima T, Saito Y
Evaluation of left ventricular diastolic function by fractional area change using cine cardiovascular magnetic resonance: a feasibility study.
J Cardiovasc Magn Reson.
8. Okayama S, Soeda T, Kawakami R, Takami Y, Somekawa S, Ueda T, Sugawara Y, Matsumoto T, Sung JH, Nishida T, Uemura S, Saito Y
Evaluation of coronary artery disease and cardiac morphology and function in patients with hypertrophic cardiomyopathy, using cardiac computed tomography.
Heart Vessels. 2013 Dec 11. [Epub ahead of print]
9. Okayama S, Uemura S, Saito Y.
Evaluation of epicardial and intra-myocardial fat in a patient with mi tochondrial cardiomyopathy.
Int J Cardiol. 167: e43-5, 2013.
10. Okayama S, Uemura S, Saito Y.
Hypertrophic cardiomyopathy and mesenteric venous thrombosis in a patient with Klinefelter syndrome.
Int J Cardiol. 166: e50-2, 2013.
11. Soeda T, Uemura S, Saito Y, Mizuno K, Jang IK.
Optical Coherence Tomography and Coronary Plaque Characterization.
J Jpn Coron Assoc. 19: 307-314, 2013.
12. Ueda T, Kawakami R, Horii M, Sugawara Y, Matsumoto T, Okada S, Nishida T, Soeda T, Okayama S, Somekawa S, Takeda Y, Watanabe M, Kawata H, Uemura S, Saito Y
High mean corpuscular volume (MCV) is a new predictor of prognosis in patients with acute decompensated heart failure.
Circ. J. 77: 2766-71, 2013.
13. Yamano S, Horii M, Takami T, Sakuma M, Morimoto T, Okada S, Taoka T, Kichikawa K, Sasamura H, Itoh H, Furuya Y, Ueno S, Imamura T, Sugiyama S, Ogawa H, Saito Y.
Comparison between angiotensin converting enzyme inhibitors and angiotensin receptor blockers on the risk of stroke recurrence and longitudinal progression of white matter lesions and silent brain infarcts on MRI (CEREBRAL study): Rationale, design, and methodology.
Int J Stroke, 2013 Jul 9. doi: 10.1111/ijs.12085. [Epub ahead of print]

共同研究(2013年)

1. Kubo T, Akasaka T, Shite J, Suzuki T, Uemura S, Yu B, Kozuma K, Kitabata H, Shinke T, Habara M, Saito Y, Hou J, Suzuki N, Zhang S.
OCT compared with IVUS in a coronary lesion assessment: the OPUS-CLASS study.
JACC Cardiovasc Imaging. 2013 Oct;6(10):1095-1104. doi: 10.1016/j.jcmg.2013.04.014. Epub 2013 Sep 4.
2. Soejima H, Ogawa H, Morimoto T, Nakayama M, Okada S, Sakuma M, Uemura S, Kanauchi M, Doi N, Jinnouchi H, Sugiyama S, Waki M, Saito Y; JPAD Trial Investigators.
Aspirin possibly reduces cerebrovascular events in type 2 diabetic patients with higher C-reactive protein level: subanalysis from the JPAD trial.
J Cardiol. 2013 Sep;62(3):165-70. doi: 10.1016/j.jjcc.2013.03.015. Epub 2013 Jun 16.
3. Arimura T, Onoue K, Takahashi-Tanaka Y, Ishikawa T, Kuwahara M, Setou M, Shigenobu S, Yamaguchi K, Bertrand AT, Machida N, Takayama K, Fukusato M, Tanaka R, Somekawa S, Nakano T, Yamane Y, Kuba K, Imai Y, Saito Y, Bonne G, Kimura A.
Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations.
Cardiovasc Res. 99: 382-94, 2013.
4. Hamm A, Veschini L, Takeda Y, Costa S, Delamarre E,Squadrito ML, Henze AT, Wenes M, Serneels J, Pucci F, Roncal C, Anisimov A, Alitalo K, De Palma M, Mazzone M.
PHD2 regulates arteriogenic macrophages through TIE2 signalling.
EMBO Mol Med. 5: 843-57, 2013.

原著(2012年 筆頭著者アルファベット順)

1. Asai O, Nakatani K, Tanaka T, Sakan H, Imura A, Yoshimoto S, Samejima KI, Yamaguchi Y, Matsui M, Akai Y, Konishi N, Iwano M, Nabeshima Y, Saito Y.
Decreased renal α-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion.
Kidney Int. 81(6):539-547, 2012.
2. Iwano M, Yamaguchi Y,Iwamoto T, Nakatani K, Matsui M, Kubo A, Akai Y, Mori T, Saito Y
Urinary FSP1 Is a Biomarker of Crescentic GN.
J Am Soc Nephrol. 23(2):209-214, 2012.
3. Kawata H, Uesugi Y, Soeda T, Takemoto Y, Sung JH, Umaki K, Kato K, Ogiwara K, Nogami K, Ishigami K, Horii M, Uemura S, Shima M, Tabata Y, Saito Y.
A new drug delivery system for intravenous coronary thrombolysis with thrombus-targeting and stealth activity recoverable by ultrasound.
J Am Coll Cardiol. 60(24):2550-2557, 2012.
4. Matsui M, Okayama S, Takitsume A, Morimoto K, Samejima K, Uemura S, Saito Y.
Heart failure associated with metastatic myocardial calcification in a hemodialysis patient with progressive calcification of the hand.
Cardiorenal Med. 2:251-255, 2012.
5. Mizuno R, Fujimoto S, Saito Y, Okamoto Y.
Optimal antihypertensive level for improvement of coronary microvascular dysfunction: the lower, the better?
Hypertension. 60(2):326-332, 2012.
6. Mori E, Akai Y, Matsumoto T, Kawaratani H, Horii M, Iwano M, Uemura S, Nonomura A, Fukui H, Saito Y.
Hepatic cyst infection in a healthy older male.
BMJ Case Rep. 2012 Mar 20;2012. pii: bcr0420114136. doi: 10.1136/bcr.04.2011.4136.
7. Nishida T, Nakajima T, Kaitani K, Takitsume A, Soeda T, Okayama S, Somekawa S, Takeda Y, Ishigami KI, Kawata H, Kawakami R, Horii M, Uemura S, Saito Y.
Non-contact mapping system accurately localizes right-sided accessory pathways in type B Wolff-Parkinson-White syndrome.
Europace. 14(5):752-760, 2012.
8. Okayama S, Soeda T, Kawakami R, Takami Y, Somekawa S, Ueda T, Sugawara Y, Matsumoto T, Sung JH, Nishida T, Uemura S, Saito Y
Evaluation of coronary artery disease and cardiac morphology and function in patients with hypertrophic cardiomyopathy, using cardiac computed tomography.
Heart Vessels. 2013 Dec 11. [Epub ahead of print]
9. Okayama S, Seno A, Soeda T, Takami Y, Kawakami R, Somekawa S, Ishigami K, Takeda Y, Kawata H, Horii M, Uemura S, Saito Y
Optimization of energy level for coronary angiography with dual-energy and dual-source computed tomography.
Int J Cardiovasc Imaging. 28(4):901-909, 2012.
10. Okayama S, Soeda T, Takami Y, Kawakami R, Somekawa S, Uemura S, Saito Y.
The influence of effective energy on computed tomography number depends on tissue characteristics in monoenergetic cardiac imaging.
Radiol Res Pract. 2012;2012:150980. doi: 10.1155/2012/150980. Epub 2012 Oct 9.
11. Samejima K, Nakatani K, Suzuki D, Asai O, Sakan H, Yoshimoto S, Yamaguchi Y, Matsui M, Akai Y, Toyoda M, Iwano M, Saito Y.
Clinical significance of fibroblast-specific protein-1 expression on podocytes in patients with focal segmental glomerulosclerosis.
Nephron Clin Pract. 120(1):c1-7, 2012
12. Somekawa S, Imagawa K, Hayashi H, Sakabe M, Ioka T, Sato GE, Inada K, Iwamoto T, Mori T, Uemura S, Nakagawa O, Saito Y
Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.
PNAS.109(30):12064-12069, 2012.
13. Takami T, Yamano S, Okada S, Sakuma M, Morimoto T, Hashimoto H, Somekawa S, Saito Y.
Major risk factors for the appearance of white-matter lesions on MRI in hypertensive patients with controlled blood pressure.
Vasc Health Risk Manag. 8:169-176, 2012.
14. Uemura S, Ishigami K, Soeda T, Okayama S, Sung JH, Nakagawa H, Somekawa S, Takeda Y, Kawata H, Horii M, Saito Y
Thin-Cap Fibroatheroma and Microchannel Findings in Optical Coherence Tomography Correlate with Subsequent Progression of Coronary Atheromatous Plaques.
Eur Heart J. 33(1):78-85, 2012.

共同研究(2012年)

1. Doi M, Matsui H, Takeda Y, Saito Y, Takeda M, Matsunari Y, Nishio K, Shima M, Banno F, Akiyama M, Kokame K, Miyata T, Sugimoto M.
ADAMTS13 safeguards the myocardium in a mouse model of acute myocardial infarction.
Thromb Haemost. 108(6):1236-1238, 2012.
2. Kato K, Yonetsu T, Kim SJ, Xing L, Lee H, McNulty I, Yeh RW, Sakhuja R, Zhang S, Uemura S, Yu B, Mizuno K, Jang IK.
Nonculprit plaques in patients with acute coronary syndromes have more vulnerable features compared with those with non-acute coronary syndromes: a 3-vessel optical coherence tomography study.
Circ Cardiovasc Imaging. 5(4):433-440, 2012.
3. Katoh D, Mizuno Y, Harada E, Ito T, Morikawa Y, Nakagawa H, Saito Y, Yoshimura M, Yasue H.
High incidence of provoked coronary spasm in the presence of a stent after myocardial infarction: therapeutic and prognostic implications.
Coron Artery Dis. 23(3):141-145, 2012.
4. Leite de Oliveira R, Deschoemaeker S, Henze AT, Debackere K, Finisguerra V, Takeda Y, Roncal C, Dettori D, Tack E, Jonsson Y, Veschini L, Peeters A, Anisimov A, Hofmann M, Alitalo K, Baes M, D'hooge J, Carmeliet P, Mazzone M.
Gene-targeting of phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Cancer Cell. 22(2):263-277, 2012.
5. Tearney GJ, Regar E, Akasaka T, Adriaenssens T, Barlis P, Bezerra HG, Bouma B, Bruining N, Cho JM, Chowdhary S, Costa MA, de Silva R, Dijkstra J, Di Mario C, Dudek D, Falk E, Feldman MD, Fitzgerald P, Garcia-Garcia HM, Gonzalo N, Granada JF, Guagliumi G, Holm NR, Honda Y, Ikeno F, Kawasaki M, Kochman J, Koltowski L, Kubo T, Kume T, Kyono H, Lam CC, Lamouche G, Lee DP, Leon MB, Maehara A, Manfrini O, Mintz GS, Mizuno K, Morel MA, Nadkarni S, Okura H, Otake H, Pietrasik A, Prati F, Raber L, Radu MD, Rieber J, Riga M, Rollins A, Rosenberg M, Sirbu V, Serruys PW, Shimada K, Shinke T, Shite J, Siegel E, Sonoda S, Suter M, Takarada S, Tanaka A, Terashima M, Thim T, Uemura S, Ughi GJ, van Beusekom HM, van der Steen AF, van Es GA, van Soest G, Virmani R, Waxman S, Weissman NJ, Weisz G; International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT).
Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation.
J Am Coll Cardiol. 59(12):1058-1072, 2012.
6. Yonetsu T, Kato K, Kim SJ, Xing L, Jia H, McNulty I, Lee H, Zhang S, Uemura S, Jang Y, Kang SJ, Park SJ, Lee S, Yu B, Kakuta T, Jang IK.
Predictors for neoatherosclerosis: a retrospective observational study from the optical coherence tomography registry.
Circ Cardiovasc Imaging. 5(5):660-666, 2012.
7. Yonetsu T, Kim JS, Kato K, Kim SJ, Xing L, Yeh RW, Sakhuja R, McNulty I, Lee H, Zhang S, Uemura S, Yu B, Kakuta T, Jang IK.
Comparison of incidence and time course of neoatherosclerosis between bare metal stents and drug-eluting stents using optical coherence tomography.
Am J Cardiol. 110(7):933-939, 2012.

原著(2011年 筆頭著者アルファベット順)

1. Kubo A, Stull R, Takeuchi M, Bonham K, Gouon-Evans V, Sho M, Iwano M, Saito Y, Keller G, Snodgrass R
Pdx1 and Ngn3 Overexpression Enhances Pancreatic Differentiation of Mouse ES Cell-Derived Endoderm Population.
PLoS One. 6(9):e24058, 2011.
2. Maisel AS, Nakao K, Ponikowski P, Peacock WF, Yoshimura M, Suzuki T, Tsutamoto T, Filippatos GS, Saito Y, Seino Y, Minamino N, Hirata Y, Mukoyama M, Nishikimi T, Nagai R
Japanese-Western consensus meeting on biomarkers.
Int Heart J. 52(5):253-265, 2011.
3. Morikawa Y, Uemura S, Ishigami K, Soeda T, Okayama S, Takemoto Y, Onoue K, Somekawa S, Nishida T, Takeda Y, Kawata H, Horii M, Saito Y
Morphological features of coronary arteries in patients with coronary spastic angina: Assessment with intracoronary optical coherence tomography.
Int J Cardiol. 146(3):334-340, 2011.
4. Okada S, Morimoto T, Ogawa H, Kanauchi M, Nakayama M, Uemura S, Doi N, Jinnouchi H, Waki M, Soejima H, Sakuma M, Saito Y;for the Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial Investigators.
Differential Effect of Low-Dose Aspirin for Primary Prevention of Atherosclerotic Events in Diabetic Management: A Subanalysis of the JPAD Trial.
Diabetes Care. 34(6):1277-1283, 2011.
6. Okayama S, Ayako S, Somekawa S, Uemura S, Kubota Y, Saito Y
Feasibility of dual gradient-echo in-phase and opposed-phase magnetic resonance imaging for the evaluation of epicardial fat.
Acta Radiol. 52(7):723-729, 2011.
7. Okayama S, Soeda T, Seno A, Watanabe M, Nakajima T, Uemura S, Saito Y
Rare Concurrence of Apical Hypertrophic Cardiomyopathy and Effusive Constrictive Pericarditis.
Open Cardiovasc Med J. 5:99-102, 2011.
8. Okayama S, Uemura S, Soeda T, Onoue K, Somekawa S, Ishigami K, Watanabe M, Nakajima T, Fujimoto S, Saito Y
Clinical significance of papillary muscle late enhancement detected via cardiac magnetic resonance imaging in patients with single old myocardial infarction.
Int J Cardiol. 146(1):73-79, 2011.
9. Saito Y, Kishimoto I, Nakao K
Roles of guanylyl cyclase-A signaling in the cardiovascular system.
Can J Physiol Pharmacol. 89(8):551-556, 2011.
10. Saito Y, Morimoto T, Ogawa H, Nakayama M, Uemura S, Doi N, Jinnouchi H, Waki M, Soejima H, Sugiyama S, Okada S, Akai Y
Low-dose Aspirin Therapy in Patients With Type 2 Diabetes Mellitus and Reduced Glomerular Filtration Rate: Subanalysis from the JPAD Trial.
Diabetes Care. 34(2):280-285, 2011.
11. Sakan H, Okayama S, Uemura S, Somekawa S, Ishigami K, Takeda Y, Kawata H, Horii M, Fujimoto S, Saito Y
Atrial right-to-left shunt without pulmonary hypertension in a patient with biventricular non-compaction cardiomyopathy accompanied by ventricular and atrial septal defects.
Intern Med. 50(16):1747-1751, 2011.
12. Soeda T, Okayama S, Seno A, Kawakami R, Somekawa S, Takeda Y, Uemura S, Saito Y.
Contrast-enhanced computed tomographic and echocardiographic detection of intra-aortic free floating thrombus causing acute myocardial infarction
J Cardiovasc Comput Tomogr. 5(1):63-65, 2011.
13. Soeda T, Uemura S, Morikawa Y, Ishigami K, Okayama S, Hee SJ, Nishida T, Onoue K, Somekawa S, Takeda Y, Kawata H, Horii M, Saito Y.
Diagnostic accuracy of dual-source computed tomography in the characterization of coronary atherosclerotic plaques: comparison with intravascular optical coherence tomography.
Int J Cardiol. 148(3):313-318, 2011 Epub 2009 Dec 11.
14. Soeda T, Uemura S, Okayama S, Kawakami R, Sugawara Y, Nakagawa H, Matsumoto T, Sung JH, Nishida T, Senoo A, Somekawa S, Takeda Y, Ishigami K, Kawata H, Horii M, Saito Y
Intensive lipid-lowering therapy with rosuvastatin stabilizes lipid-rich coronary plaques. -Evaluation using dual-source computed tomography.-.
Circ J. 75(11):2621-2627, 2011.
15. Takami T, Saito Y.
Effects of smoking cessation on central blood pressure and arterial stiffness.
Vasc Health Risk Manag. 7:633-638, 2011.
17. Takeda Y, Costa S, Delamarre E, Roncal C, Leite de Oliveira R, Squadrito ML, Finisguerra V, Deschoemaeker S, Bruyere F, Wenes M, Hamm A, Serneels J, Magat J, Bhattacharyya T, Anisimov A, Jordan BF, Alitalo K, Maxwell P, Gallez B, Zhuang ZW, Saito Y, Simons M, De Palma M, Mazzone M
Macrophage Skewing by PHD2 Haplodeficiency Prevents Ischemia by Inducing Arteriogenesis.
Nature. 479(7371):122-126, 2011.
18. Waki ML, Onoue K, Takahashi T, Goto K, Saito Y, Inami K, Makita I, Angata Y, Suzuki T, Yamashita M, Sato N, Nakamura S, Yuki D, Sugiura Y, Zaima N, Goto-Inoue N, Hayasaka T, Shimomura Y, Setou M
Investigation by imaging mass spectrometry of biomarker candidates for aging in the hair cortex.
PLoS One. 6(10):e26721, 2011.
19. Zaima N, Sasaki T, Tanaka H, Cheng XW, Onoue K, Hayasaka T, Goto-Inoue N, Enomoto H, Unno N, Kuzuya M, Setou M.
Imaging mass spectrometry-based histopathologic examination of atherosclerotic lesions.
Atherosclerosis. 217(2):427-432, 2011.

原著(2010年 筆頭著者アルファベット順)

1. Harada K, Akai Y, Sakan H, Yamaguchi Y, Nakatani K, Iwano M, Saito Y
Resolution of mesangial light chain deposits 3 years after high-dose melphalan with autologous peripheral blood stem cell transplantation.
Clin Nephrol. 74(5):384-348, 2010.
2. Harada K, Miyamoto Y, Morisaki H, Ohta N, Yamanaka I, Kokubo Y, Makino H, Harada-Shiba M, Okayama A, Tomoike H, Okamura T, Saito Y, Yoshimasa Y, and Morisaki T
A novel Thr56Met mutation of the autosomal recessive hypercholesterolemia gene associated with hypercholesterolemia.
J Atheroscler Thromb. 26;17(2):131-140, 2010.
3. Kubo A, Kim Y. H, Irion S, Kasuda S, Takeuchi M, Ohashi K, Iwano M, Dohi Y, Saito Y, Snodgrass R, Keller G
The Homeobox Gene HEX Regulates Hepatocyte Differentiation from ES cell-Derived Endoderm.
Hepatology. 51(2):633-641, 2010.
4. Li Y, Saito Y, Kuwahara K, Rong X, Kishimoto I, Harada M, Horiuchi M, Murray M, Nakao K
Vasodilator therapy with hydralazine induces angiotensin AT receptor-mediated cardiomyocyte growth in mice lacking guanylyl cyclase-A.
Br J Pharmacol. 159(5):1133-1142, 2010.
5. Nakatani K, Yoshimoto S, Iwano M, Asai O, Samejima K, Sakan H, Terada M, Hasegawa H, Nose M, Saito Y.
Fractalkine expression and CD16+ monocyte accumulation in glomerular lesions: association with their severity and diversity in lupus models.
Am J Physiol Renal Physiol. 299(1):F207-216, 2010.
6. Okada S, Hiuge A, Makino H, Nagumo A, Takaki H, Konishi H, Goto Y, Yoshimasa Y, Miyamoto Y
Effect of exercise intervention on endothelial function and incidence of cardiovascular disease in patients with type 2 diabetes.
J Atheroscler Thromb. 17(8):828-833, 2010.
7. Okada S, Kozuka C, Masuzaki H, Yasue S, Ishii-Yonemoto T, Tanaka T, Yamamoto Y, Noguchi M, Kusakabe T, Tomita T, Fujikura J, Ebihara K, Hosoda K, Sakaue H, Kobori H, Ham M, Lee YS, Kim JB, Saito Y, Nakao K
Adipose tissue-specific dysregulation of angiotensinogen by oxidative stress in obesity.
Metabolism. 59(9):1241-1251, 2010.
8. Okayama S, Fujimoto S, Tsutsumi T, Onoue K, Horii M, Uemura S, Sakaguchi Y, and Saito Y
A pediatric case of hypertrophic cardiomyopathy with mid-ventricular obstruction incidentally detected by electrocardiography.
JC Cases. 1(2):67-70, 2010.
9. Okayama S, Kawata H, Sung JH, Okada S, Nishida T, Onoue K, Soeda T, Uemura S, and Saito Y
Dual-single photon emission computed tomography and contrast-enhanced magnetic resonance imaging to evaluate dissimilar features of apical hypertrophic cardiomyopathy.
Cardiol J. 17(3):306-311, 2010.
11. Okayama S, Uemura S, Soeda T, Seno A, Onoue K, Ishigami K, Horii M, Saito Y
Congenital isolated biventricular diverticula evaluated by cardiac computed tomography and magnetic resonance imaging.
Heart Lung Circ. 19(10):630-632, 2010.
12. Okayama S, Uemura S, Sugimoto H, Enomoto S, Onoue K, Omori S, Soeda T, Somekawa S, Ishigami K, Watanabe M, Nakajima T, Kubota Y, Saito Y
Dual Gradient-echo In-phase and Opposed-phase Magnetic Resonance Imaging to Evaluate Lipomatous Metaplasia in Patients with Old Myocardial Infarction.
Magn Reson Med Sci. 9(2):85-89, 2010.
13. Okayama S, Uemura S, Watanabe M, Morikawa Y, Onoue K, Soeda T, Iwama H, Somekawa S, Takeda Y, Uramoto H, Kobayashi Y, Saito Y
Novel application of black-blood echo-planar imaging to the assessment of myocardial infarction.
Heart and Vessel. 25(2):104-112, 2010.
14. Onoue K, Zaima N, Sugiura Y, Isojima T, Okayama S, Horii M, Akai Y, Uemura S, Takemura G, Sakuraba H, Sakaguchi Y, Setou M, Saito Y.
Imaging Mass Spectrometry to Accurately Diagnose Fabry’s Disease.
Circ J. 24;75(1):221-223, 2010.
18. Uesugi Y, Kawata H, Jo J, Saito Y, Tabata Y
An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy.
J Control Release. 15;147(2):269-277, 2010.
19. Yamazaki Y, Imura A, Urakawa I, Shimada T, Murakami J, Aono Y, Hasegawa H, Yamashita T, Nakatani K, Saito Y, Okamoto N, Kurumatani N, Namba N, Kitaoka T, Ozono K, Sakai T, Hataya H, Ichikawa S, Imel EA, Econs MJ, Nabeshima Y.
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects.
Biochem Biophys Res Commun. 30;398(3):513-518, 2010.

原著(2009年 筆頭著者アルファベット順)

1. Ishigami K, Uemura S, Morikawa Y, Soeda T, Okayama S, Nishida T, Takemoto Y, Onoue K, Somekawa S, Takeda Y, Kawata H, Horii M, Saito Y
Long term follow-up of neointimal coverage of sirolimus-eluting stents: Evaluation with optical coherencetomography.
Circ J. 3(12):2300-2307, 2009.
2. Li Y, Saito Y, Kuwahara K, Rong X, Kishimoto I, Harada M, Adachi Y, Nakanishi M, Kinoshita H, Horiuchi M, Murray M, Nakao K
Guanylyl cyclase-A inhibits angiotensin II type 2 receptor-mediated pro-hypertrophic signaling in the heart.
Endocrinology. 150(8):3759-3765, 2009.
3. Motoyama H, Ogawa S, Kubo A, Miwa S, Tagawa Y, Miyagawa S
In vitro reprogramming of adult hepatocytes into insulin-producing cells without viral vectors.
Biochem Biophys Res Commun. 385:123-128, 2009.
4. Morikawa Y, Uemura S, Ishigami K, Soeda T, Okayama S, Takemoto Y, Onoue K, Somekawa S, Nishida T, Takeda Y, Kawata H, Horii M, Saito Y
Morphological features of coronary arteries in patients with coronary spastic angina: Assessment with intracoronary optical coherence tomography.
Int J Cardiol. 146(3):334-340, 2011 Epub 2009 Aug 27.
5. Nakagawa H, Morikawa Y, Mizuno Y, Harada E, Ito T, Matsui K, Saito Y, Yasue H
Coronary Spasm Preferentially Occurs at Branch Points: An Angiographic Comparison With Atherosclerotic Plaque.
Circ Cardiovasc Intervent. 2:97-104, 2009.
6. Okayama S, Matsui M, Somekawa S, Iwano M, Saito Y
Non-contrast MRI for the evaluation of hydronephrotic and dysfunctioning kidney secondary to testicular cancer.
Ren Fail. 31(2):153-158, 2009.
7. Onoue K, Uemura S, Takeda Y, Somekawa S, Iwama H, Nishida T, Morikawa Y, Nakagawa H, Tsutsumi T, Sung J. H, Takemoto Y, Soeda T, Okayama S, Ishigami K, Kawata H, Horii M, Nakajima T, Saito Y
Usefulness of soluble Fms-like tyrosine kinase 1 as a biomarker of acute severe heart failure in patients with acute myocardial infarction.
Am J Cardiol. 104(11):1478-1483, 2009.
8. Onoue K, Uemura S, Takeda Y, Somekawa S, Iwama H, Imagawa K, Nishida T, Morikawa Y, Takemoto Y, Asai O, Soeda T, Okayama S, Ishigami K, Nakatani K, Kawata H, Horii M, Nakajima T, Akai Y, Iwano M, Saito Y
Reduction of circulating soluble fms-like tyrosine kinase-1 plays a significant role in renal dysfunction-associated aggravation of atherosclerosis.
Circulation. 15;120(24):2470-2477, 2009.
9. Somekawa S, Imagawa K, Naya N, Takemoto Y, Onoue K, Okayama S, Takeda Y, Kawata H, Horii M, Nakajima T, Uemura S, Mochizuki N, Saito Y
Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor.
Endocrinology. 50(7):3110-3117, 2009.
10. Takaoka M, Nagata D, Kihara S, Shimomura I, Kimura Y,Tabata Y, Saito Y, Nagai R, and Sata M
Periadventitial adipose tissue plays a critical role in vascular remodeling.
Circ Res. 105(9):906-911, 2009.
11. Takeda Y, Uemura S, Iwama H, Imagawa K, Nishida T, Onoue K, Takemoto Y, Soeda T, Okayama S, Somekawa S, Ishigami K, Takaoka M, Kawata H, Kubo A, Horii M, Nakajima T, Saito Y
Treatment with recombinant placental growth factor (PlGF) enhances both angiogensis and arteriogenesis and improves survival after myocardial infarction.
Circ J. 73(9):1674-1682, 2009.
12. Takemoto Y, Kawata H, Soeda T, Imagawa K, Somekawa S, Takeda Y, Uemura S, Matsumoto M, Fujimura Y, Jo J, Kimura Y, Tabata Y, Saito Y
Human placental ectonucleoside triphosphate diphosphohydrolase gene transfer via gelatin-coated stents prevents in-stent thrombosis.
Arterioscler Thromb Vasc Biol. 29(6):857-862, 2009.
13. Yamaguchi Y, Iwano M, Suzuki D, Nakatani K, Kimura K, Harada K, Kubo A, Akai Y, Toyoda M, Kanauchi M, Eric G Neilson, SaitoY
Epithelial-mesenchymal transition as an explanation for podocyte depletion in diabetic nephropathy.
Am J Kidney Dis. 54(4):653-664, 2009.

原著(2008年 筆頭著者アルファベット順)

1. Horii M, Uemura S, Uemura M, Matsumoto M, Ishizashi H, Imagawa K, Iwama H, Takeda Y, Kawata H, Nakajima T, Fujimura Y, Saito Y
Acute Myocardial Infarction as a Systemic Prothrombotic Condition Evidenced by Increased von Willebrand Factor Protein Over ADAMTS13 Activity in Coronary and Systemic Circulation.
Heart and Vessel. 23(5):301-307, 2008.
2. Harada K, Akai Y, Yamaguchi Y, Kimura K, Nishitani Y, Nakatani K, Iwano M, Saito Y
Prediction of corticosteroid responsiveness based on fibroblast-specific protein 1 (FSP1) in patients with IgA nephropathy.
Nephrol Dial Transplant. 23(10):3152-3159, 2008.
3. Harada K, Akai Y, Koyama S, Ikenaka Y, Saito Y
A case of autoimmune hepatitis exacerbated by the administration of etanercept in the patient with rheumatoid arthritis.
Clin Rheumatol. 27(8):1063-1066, 2008.
4. Kasuda S, Kubo A, Sakurai Y, Irion S, Ohashi K, Tatsumi K, Nakajima Y, Saito Y, Hakake K, Pipe SW, Shima M, Yoshioka A
Establishment of embryonic stem cells secreting human factor VIII for cell-based treatment of hemophilia A.
J Thromb Haemost. 6(8):1352-1359, 2008.
5. Matoba S, Tatsumi T, Murohara T, Imaizumi T, Katsuda Y, Ito M, Saito Y, Uemura S, Suzuki H, Fukumoto S, Yamamoto Y, Onodera R, Teramukai S, Fukushima M, Matsubara H
Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia.
Am Heart J. 156:1010-1018, 2008.
6. Ogawa H, Nakayama M, Morimoto T, Uemura S, Kanauchi M, Doi N, Jinnouchi H, Sugiyama S, Saito Y
Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial.
JAMA. 300(18):2134-2141, 2008.
7. Okayama S, Hirai T, Yamashita N, Somekawa S, Iwano M, Uemura S, Kanauchi M, Saito Y
Contrast-enhanced ultrasonography with Sonazoid for evaluation of renal microcirculation.
J Med Ultrasonics. 35:183-189, 2008.
9. Okayama S, Uemura S, Nishida T, Morikawa Y, Onoue K, Takemoto Y, Soeda T, Somekawa S, Ishigami K, Takeda Y, Horii M, Kawata H, Takaoka M, Nakajima T, Saito Y
Progression of non-culprit coronary artery atherosclerosis after acute myocardial infarction in comparison with stable angina pectoris.
J Atheroscler Thromb. 15(5):228-234, 2008.
10. Q Zhang, Saito Y, Naya N, Imagawa K, Somekawa S, Kawata H, Takeda Y, Uemura S, Kishimoto I, Nakao K
The Specific Mineralocorticoid Receptor Blocker Eplerenone Attenuates Left Ventricular Remodeling in Mice Lacking the Gene Encoding Guanylyl Cyclase-A
Hypertens Res. 31(6):1251-1256, 2008.
11. Yasue H, Mizuno Y, Harada E, Itoh T, Nakagawa H, Nakayama M, Ogawa H, Tayama S, Honda T, Hokimoto S, Ohshima S, Hokamura Y, Kugiyama K, Horie M, Yoshimura M, Harada M, Uemura S, Saito Y
Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, fluvastatin, on coronary spasm after withdrawal of calcium-channel blockers.
J Am Coll Cardiol. 51(18):1742-1748, 2008.

原著(2007年 筆頭著者アルファベット順)

1. Higgins DF,Kimura K,Bernhardt WM,Shrimanker N,Akai Y,Hohenstein B,Saito Y, Johnson RS,Kretzler M,Cohen CD,Eckardt KU,Iwano M,Haase VH
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.
J Clin Invest. 117(12):3810-3820,2007.
2. Kanauchi M, Kanauchi K, Inoue T, Kimura K, Saito Y.
Surrogate markers of insulin resistance in assessing individuals with new categories "prehypertension" and "prediabetes".
Clin Chem Lab Med. 45(1):35-39, 2007.
3. Kawata H,Naya N,Takemoto Y,Uemura S,Nakajima T,Horii M,Takeda Y,Fujimoto S,Yamashita A,Asada Y,Saito Y
Ultrasound accelerates thrombolysis of acutely induced platelet-rich thrombi similar to those in acute myocardial infarction.
Circ J. 71(10):1643-1648,2007.
4. Kitakaze M, Asakura M, Kim J, Shintani Y, Asanuma H, Hamasaki T, Seguchi O, Myoishi M, Minamino T, Ohara T, Nagai Y, Nanto S, Watanabe K, Fukuzawa S, Hirayama A, Nakamura N, Kimura K, Fujii K, Ishihara M, Saito Y, Tomoike H, Kitamura S; J-WIND investigators.
Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials.
Lancet. 370 (9597):1483-1493, 2007.
5. Kimura K, Yamaguchi Y, Horii M, Kawata H, Yamamoto H, Uemura S, Saito Y.
ANP is Cleared Much Faster than BNP in Patients with Congestive Heart Failure.
Eur J Clin Pharmacol. 63(7):699-702, 2007.
6. Kuratomi S, Kuratomi A, Kuwahara K, Ishii TM, Nakao K, Saito Y, Takano M.
NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes.
Biochem Biophys Res Commun. 353(1):67-73, 2007.
7. Morimoto T,Nakayama M,Saito Y,Ogawa H
Aspirin for primary prevention of atherosclerotic disease in Japan.
J Atheroscler Thromb. 14(4):159-166,2007.
8. Nakatani K, Qu WM, Zhang MC, Fujii H, Furukawa H, Miyazaki T, Iwano M, Saito Y, Nose M, Ono M.
A Genetic Locus Controlling Aging-sensitive Regression of B Lymphopoiesis in an Autoimmune-prone MRL/lpr Strain of Mice.
Scand J Immunol. 66(6):654-661,2007.
9. Nakanishi M, Harada M, Kishimoto I, Kuwahara K, Kawakami R, Nakagawa Y, Yasuno S, Usami S, Kinoshita H, Adachi Y, Fukamizu A, Saito Y, Nakao K.
Genetic Disruption of Angiotensin II Type 1a Receptor Improves Long-Term Survival of Mice With Chronic Severe Aortic Regurgitation.
Circ J. 71(8):1310-1316, 2007.
10. Nishijima T, Nakayama M, Yoshimura M, Abe K, Yamamuro M, Suzuki S, Shono M, Sugiyama S, Saito Y, Miyamoto Y, Nakao K, Yasue H, Ogawa H.
The endothelial nitric oxide synthase gene -786T/C polymorphism is a predictive factor for reattacks of coronary spasm.
Pharmacogenet Genomics. 17(8):581-587, 2007.
11. Okayama S, Uemura S, Saito Y
Detection of infarct-related myocardial edema using cardiac diffusion-weighted magnetic resonance imaging.
Int J Cardiol. Dec 17, 2007.
12. Shimasaki Y, Saito Y, Yoshimura M, Kamitani S, Miyamoto Y, Masuda I, Nakayama M, Mizuno Y, Ogawa H, Yasue H, Nakao K.
The effects of long-term smoking on endothelial nitric oxide synthase mRNA expression in human platelets as detected with real-time quantitative RT-PCR.
Clin Appl Thromb Hemost. 13(1):43-51, 2007.
14. Tatsumi T, Ashihara E, Yasui T, Matsunaga S, Kido A, Sasada Y, Nishikawa S, Hadase M, Koide M, Nakamura R, Irie H, Ito K, Matsui A, Matsui H, Katamura M, Kusuoka S, Matoba S, Okayama S, Horii M, Uemura S, Shimazaki C, Tsuji H, Saito Y, Matsubara H.
Intracoronary transplantation of non-expanded peripheral blood-derived mononuclear cells promotes improvement of cardiac function in patients with acute myocardial infarction.
Circ J. 71(8):1199-1207, 2007.
15. Yoshimoto S, Nakatani K, Iwano M, Asai O, Samejima K, Sakan H, Terada M, Harada K, Akai Y, Shiiki H, Nose M, Saito Y.
Elevated levels of fractalkine expression and accumulation of CD16+monocytes in glomeruli of active lupus nephritis
Am J Kidney Dis. 50(1):47-58, 2007.

原著(2006年 筆頭著者アルファベット順)

1. Iwama H, Naya N, Imagawa K, Takemoto Y, Asai O, Onoue K, Okayama S, Somekawa S, Kida Y, Takeda Y, Takaoka H, Kawata M, Horii M, Nakajima T, Doi N, Saito Y.
Cardiac expression of placental growth factor predicts the improvement of chronic phase left ventricular function in patients with acute myocardial infarction.
J. Am. Coll. Cardiol. 47:1559-1567, 2006.
2. Imagawa K, Okayama S, Takaoka M, Kawata H, Naya N, Nakajima T, Horii M, Uemura S, Saito Y.
Inhibitory effect of efonidipine on aldosterone synthesis and secretion in human adrenocarcinoma (H295R) cells.
J. Cardiovasc. Pharmacol. 47:133-138, 2006.
3. Kanauchi M, Kanauchi K, Kimura K, Inoue T, Saito Y.
Utility of elevated 2-hour postload plasma glucose as an alternative to elevated fasting glucose as a criterion for the metabolic syndrome.
Metabolism. 55:1323-1326, 2006.
4. Kanauchi M, Kanauchi K, Kimura K, Inoue T, Saito Y.
Associations of chronic kidney disease with the metabolic syndrome in non-diabetic elderly.
Nephrol Dial Transplant. 2006.
5. Kin T, Yamano S, Sakurai R, Kajitani M, Okahashi Y, Nishiura N, Saito Y, Ueno S.
Carotid Atherosclerosis is Associated with Brain Atrophy in Japanese Elders.
Gerontology. 53:1-6, 2006.
6. Mizuno R, Fujimoto S, Saito Y, Nakamura S.
Non-Invasive Quantitation of Myocardial Fibrosis Using Combined Tissue Harmonic Imaging and Integrated Backscatter Analysis in Dilated Cardiomyopathy.
Cardiology. 108:11-17, 2006.
7. Nakagawa Y, Kuwahara K, Harada M, Takahashi N, Yasuno S, Adachi Y, Kawakami R, Nakanishi M, Tanimoto K, Usami S, Kinoshita H, Saito Y, Nakao K.
Class II HDACs mediate CaMK-dependent signaling to NRSFin ventricular myocytes.
J. Mol. Cell Cardiol. 2006.
8. Nakayama M, Yoshimura M, Sakamoto T, Abe K, Yamamuro M, Shono M, Suzuki S, Nishijima T.
A -786T>C polymorphism in the endothelial nitric oxide synthase gene reduces serum nitrite/nitrate levels from the heart due to an intracoronary injection of acetylcholine.
Pharmacogenet. Genomics. 16:339-345, 2006.
9. Okayama S, Imagawa K, Noriyuki N, Iwama H, Somekawa S, Kawata H, Horii M, Nakajima T, Uemura S, Saito Y.
Blocking T-type Ca2+ channels with Efonidipine Decreased Plasma Aldosterone Concentration in Healthy Volunteers.
Hypertens. Res. 29:493-497, 2006.
10. Takaoka M, Uemura S, Kawata H, Imagawa K, Takeda Y, Nakatani K, Naya N, Horii M, Yamano S, Miyamoto Y, Yoshimasa Y, and Yoshihiko S.
Inflammatory response to acute myocardial infarction augments neointimal hyperplasia after vascular injury in a remote artery.
Arterioscler Thromb Vasc Biol. 26:2083-2089, 2006.
11. Watanabe M, Uemura S, Iwama H, Okayama S, Takeda Y, Kawata H, Horii M, Nakajima T, Hirohashi S, Kichikawa K, Ookura A, Saito Y.
Usefulness of 16-slice multislice spiral computed tomography for follow-up study of coronary stent implantation.
Circ. J. 70:691-697, 2006.
12. Yamamuro M, Yoshimura M, Nakayama M, Abe K, Shono M, Suzuki S, Sakamoto T, Saito Y, Nakao K, Yasue H, Ogawa H.
Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium.
Endocrinology. 147:1314-1321, 2006.

原著(2005年 筆頭著者アルファベット順)

1. Abe K, Nakayama M, Yoshimura M, Nakamura S, Ito T, Yamamuro M, Sakamoto T, Miyamoto Y, Yoshimasa Y, Saito Y, Nakao K, Yasue H, Ogawa H.
Increase in the transcriptional activity of the endothelial nitric oxide synthase gene with fluvastatin: relation with the -786T>C polymorphism.
Pharmacogenet Genomics. 15:29-36, 2005.
2. Biju MP., Akai Y, Shrimanker N, Haase VH.
Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent.
Am. J. Physiol. Renal Physiol. 289:F1217-1226, 2005.
3. Danno D, Fujimoto S, Yamamoto Y, Mizuno R, Maeda K, Kanno M, Fujimoto T, Matsumura M, Nakamura S.
Influence of patient/doctor relationship on the non-attendence rate of general practice, and investigation of reason for hospital non-attendance.
General Medicine. 16:17-21, 2005.
4. Fukuhara S, Sakurai A, Sano H, Yamagishi A, Somekawa S, Takakura N, Saito Y, Kangawa K, Mochizuki N.
Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway.
Mol. Cell Biol. 25:136-146,2005.
5. Fukuhara S, Tomita S, Nakatani T, Yutani C, Kitamura S.
Endogenous bone-marrow-derived stem cells contribute only a small proportion of regenerated myocardium in the acute infarction model.
J. Heart Lung Transplant. 24:67-72, 2005.
6. Hamano K, Katafuchi T, Kikumoto K, Minamino N.
Calcitonin receptor-stimulating peptide-1 regulates ion transport and growth of renal epithelial cell line LLC-PK1.
Biochem. Biophys. Res. Commun. 330: 75-80, 2005.
7. Harada K, Akai Y, Iwano M, Nakatani K, Nishino T, Fujimoto T, Shiiki H, Saito Y.
Tubulointerstitial macrophage infiltration in a patient with hypokalemic nephropathy and primary Sjogren's syndrome.
Clin Nephrol. 64: 387-390, 2005.
8. Kanauchi M, Kimura K, Kanauchi K, Saito Y.
Beta-cell function and insulin sensitivity contribute to the shape of plasma glucose curve during an oral glucose tolerance test in non-diabetic individuals.
Int J Clin Pract. 59: 427-432, 2005.
9. Matsumura N, Yamamoto K, Hirohashi R, Kitano S.
Renal tuberculosis mimicking hydronephrosis.
Intern. Med. 44: 768-,2005.
10. Nakanishi M, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakagawa Y, Tanimoto K, Yasuno S, Usami S, Li Y, Adachi Y, Fukamizu A, Garders DL, Nakao K.
Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice.
Hypertension. 46: 441-447, 2005.
11. Nishitani Y, Iwano M, Yamaguchi Y, Harada K, Nakatani K, Akai Y, Nishino T, Shiiki H, Kanauchi M, Saito Y, Neilson EG.
Fibroblast-specific protein 1 is a specific prognostic marker for renal survival in patients with IgAN.
Kidney Int. 68:1078-1085, 2005.
12. Saito Y.
Hypoglycemic attack: A rare triggering factor for takotsubo cardiomyopathy.
Intern. Med. 44:171-172, 2005.
13. Shima Y, Iwano M, Yoshizaki K, Tanaka T, Kawase I, Nishimoto N.
All-trans-Retinoic acid inhibits the development of mesangial proliferative glomerulonephritis in interleukin-6 transgenic mice.
Nephron Exp Nephrol. 100:54-62, 2005.
14. Somekawa S, Fukuhara S, Nakaoka Y, Fujita H, Saito Y, Mochizuki N.
Enhanced functional gap junction neoformation by protein kinase A-dependent and epac-dependent signal downstream of cAMP in cardiac myocytes.
Circ. Res. 97:655-662, 2005.
15. Takahashi N, Saito Y, Kuwahara K, Harada M, Tanimoto K, Nakagawa Y, Kawakami R, Nakanishi M, Yasuno S, Usami S, Yoshimura A, Nakao K.
Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes.
J. Mol. Cell Cardiol. 38:185-192, 2005.
16. Tanimoto K, Saito Y, Hamanaka I, Kuwahara K, Harada M, Takanashi N, Kawakami R, Nakagawa Y, Nakanishi M, Adachi Y, Shirakami G, Fukuda K, Yoshimura A and Nakano K.
SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo.
Circ. J. 69:1412-1417, 2005.
17. Yamaji K, Fujimoto S, Ikeda Y, Masuda K, Nakamura S, Saito Y, Yutani C.
Apoptotic myocardial cell death in the setting of arrhythmogenic right ventricular cardiomyopathy.
Acta Cardiologica. 60:465-470, 2005.
18. Yamamuro M, Yoshimura M, Nakayama M, Abe K, Shono M, Suzuki S, Sakamoto T, Saito Y, Nakao K, Yasue H and Ogawa H.
Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extrcellular sodium.
Endocrinology. 147:1314-1321, 2005.

原著(2004年 筆頭著者アルファベット順)

1. Adachi Y, Imagawa J, Suzuki Y, Yogo K, Fukazawa M, Kuromaru O, Saito Y.
G-CSF treatment increase side population cell infiltration after myocardial infarction in mice.
J. Mol. Cell. Cardiol. 36:707-710, 2004.
2. Fujimoto S, Mizuno R, Saito Y, Nakamura S.
Clinical application of wave intensity for the treatment of essential hypertension.
Heart Vessels. 19: 19-22, 2004.
3. Iwano M, Neilson EG
Mechanisms of tubulointerstitial fibrosis.
Curr. Opin. Nephrol. Hypertens. 13:279-284, 2004.
4. Kanauchi M, Kimura K, Akai Y and Saito Y.
Insulin resistance and pancreatic beta-cell function in the patients with hypertensive kidney disease.
Nephrol. Dial. Transplant. 19: 2025-2029, 2004.
5. Kakui K, Ito H, Sagawa N, Yura S, Korita D, Takemura M, Miyamoto Y, Saito Y, Nakao K, Fujii S.
Augmented endothelial nitric oxide synthase (eNOS) protein ezpression in human pregnant myometrium:possible involvement of eNOS promoter activation by estrogen via both estrogen receptor (ER)α and ERβ.
Mol. Hum. Reprod. 2:115-122, 2004.
6. Kanauchi M, Kanauchi K, Hashimoto T, Saito Y
Metabolic syndrome and new category 'pre-hypertension' in a Japanese population.
Curr Med Res Opin. 20:1365-1370, 2004.
7. Kawakami R, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Nakagawa Y, Nakanishi M, Tanimoto K, Usami S, Yasuno S, Saito Y, Kinoshita H, Ogawa Y, Nakao K.
Overexpression of brain natriuretic peptide induces excessive matrix remodeling after acute myocardial infarction in mice.
Circ. 110:3306-3312, 2004.
8. Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Hamanaka I, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K.
Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.
Endocrinology. 145:951-958, 2004.
9. Nakatani K, Fujii H, Hasegawa H, Terada M, Arita N, MR. Ito, Ono M, Takahashi S, Saiga K, Yoshimoto S, Iwano M, Shiiki H, Saito Y, Nose M.
Endothelial adhesion molecules in glomerular lesions: association with their severity and diversity in lupus models.
Kidney Int. 65:1290-1300, 2004.
10. Nakashima T, Yamano S, Sasaki R, Minami S, Doi K, Yamamoto J, Takaoka M, Saito Y.
White-coat hypertension contributes to the presence of carotid arteriosclerosis.
Hypertens. Res. 27:739-745, 2004.
11. Nakamura S, Yoshimura M, Nakayama M, Ito T, Mizuno Y, Harada E, Sakamoto T, Saito Y, Nakao K, Yasue H, Ogawa H.
Possible association of heart failure status with synthetic balance between aldosterone and dehydroepiandrosterone in human heart.
Circ. 110:1787-1793, 2004.
12. Nishizawa J, Matsumoto M, Sugita T, Matsuyama K, Tokuda Y, Yoshida K, Matsuo T, Okayama S, Fujimoto S and Saito Y.
Intravenous leiomyomatosis extending into the right ventricle association with pulmonary metastasis and extensive arteriovenous fistula.
J. Am. Coll. Surg. 198:842-843, 2004.
13. Suzuki S, Yoshimura M, Nakayama M, Mizuno Y, Harada E, Ito T, Nakamura S, Abe K, Yamamuro M, Sakamoto T, Saito Y, Nakao K, Yasue H, Ogawa H.
Plasma level of B-type natriuretic peptide as a prognostic marker after acute myocardial infarction: a long-term follow-up analysis.
Circ. 110:1387-1391, 2004.
14. Shiiki H, Saito T, Nishitani Y, Mitarai T, Yorioka N, Yoshimura A, Yokoyama H, Nishi S, Tomino Y, Kurokawa K, Sakai H.
Research Group on Progressive Renal Diseases in Japan.
Prognosis and risk factors for idiopathic membranous nephropathy with nephritic syndrome in Japan.
Kidney Int. 65:1400-1407, 2004.
15. Takeda Y, Mori T, Imabayashi H, Kiyono T, Gojo S, Miyoshi S, Hida N, Ita M, Segawa K, Ogawa S, Sakamoto M, Nakamura S, Umezawa A.
Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation.
J. Gene. Med. 6:833-845, 2004.
16. Uemura S, Watanabe M, Iwama H, Saito Y.
Extensive primary cardiac liposarcoma with multiple functional complications.
Heart. 90: e48-49, 2004.

原著(2003年 筆頭著者アルファベット順)

1. Adachi Y, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakanishi M, Nakagawa Y, Tanimoto K, Saito Y, Yasuno S, Usami S, Iwai M, Horiuchi M, Nakao K.
Angiotensin type 2 reseptor deficiency exacerbates heart failure and reduces Servival following acute myocardial infarction in mice.
Circ. 107:2406-2408, 2003.
2. Kanauchi M, Nakajima M, Kanauchi K and Saito Y.
Pancreatic beta-cell function and insulin sensitivity in Japanese subjects with impaired glucose tolerance and newly diabnosed type 2 deabetes mellitus.
Metabolism. 52:476-481, 2003.
3. Kanauchi M.
Validation of the oral glucose insulin sensitivity index to assess insulin sensitivity in Japanese subjects for use in clinical practice.
Eur J Clin Invest. 33:1022-1023, 2003.
4. Kanauchi M.
Obesity-related albuminuria and renal histology in patients with type 2 diabetes mellitus.
Nephrol Dial Transplant. 18:849-850, 2003.
5. Kanauchi M, Yamano S, Kanauchi K and Saito Y
Homeostasis model assessment of insulin resistance, quantitative insulin sensitivity check index, and oral glucose insulin sensitivity index in nonobese, nondiabetic subjects with high-nomal blood pressure.
J. Clin. Endocrinol. Metab. 88: 3444-3446, 2003.
6. Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M and Nakao K.
NRSF regulates fetal cardiac gene program and maintains normal cardiac structure and funcution.
EMBO J. 22:6310-6321, 2003.
7. Nakayama M, Yoshimura M, Sakamoto T, Shimasaki Y, Nakamura S, Ito T, Abe K, Yamamuro M, Miyamoto Y, Saito Y, Nakao K, Yasue H and Ogawa H.
Synergistic interaction of T-786 → C polymorphism in the endothelial nitric oxide synthase gene and smoking for an enhanced risk for coronary spasm.
Pharmacogenetics. 13:683-688, 2003.
8. Takahashi N, Saito Y, Kuwahara K, Harada M, Kishimoto I, Ogawa Y, Kawakami R, Nakagawa Y, Nakanishi M and Nakao K.
Angiotensin II-induced ventricular hypertrophy and extracelluar signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation.
Hypertens Res. 26:847-853, 2003.

原著(2002年 筆頭著者アルファベット順)

1. Harada K, Akai Y, Kurumatani N, Iwano M and Saito Y.
Prognostic value of urinary interleukin 6 in patients with IgA nephropathy: an 8-year follow-up study.
Nephron. 92:824-826, 2002.
2. Kanauchi M.
Cigarette smoking affects tubulointerstitial lesion in type 2 diabetes.
Diabetes. Care. 25:1486-1487, 2002.
3. Kanauchi M.
A new index of insulin sensitivity obtained from the oral glucose tolerance test applicable to advanced type 2 diabetes mellitus.
Diabetes Care. 25:1891-1892, 2002.
4. Kanauchi M, Akai Y and Hashimoto T.
Transferrinuria in type 2 diabetic patients with early nephropathy and tubulointerstitial injury.
Eur. J. Intern. Med. 13:190-193, 2002.
6. Kanauchi M, Motomiya K and Hashimoto T.
Insulin secretion and sensitivity in nonobese and obese Japanese patients with coronary artery disease.
Metabolism. 51:184-188, 2002.
7. Kanauchi M, Nishioka H and Hashimoto T.
Oxidative DNA damage and tubulointerstitial injury in diabetic nephropathy.
Nephron. 91:327-329, 2002.
8. Kanauchi M, Tsujimoto N and Hashimoto T.
Validation of simple indices to assess insulin sensitivity based on the oral blucose tolerance test in the Japanese population.
Diabetes. Res. Clin. Pract. 55:229-235, 2002.
9. Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Takahashi N, Kawakami R,Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K.
Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart.
Circ. 106:1722-1728, 2002.
10. Mizuno Y, Yasue H, Yoshimura M, Fujii H, Yamamoto N, Nakayama M, Harada E, Sakamoto T, Nakamura S, Ito T, Shimasaki Y, Ogawa H, Saito Y and Nakao K.
Effects of perindopril on aldosterone production in the failing human heart.
Am J Coll Cardiol. 89:1197-1200, 2002.
11. Ogawa E, Saito Y, Kuwahara K, Harada M, Miyamoto Y, Hamanaka I, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Kishimoto I, Naruse Y, Mori N and Nakao K.
Fibronectin signaling stimulates BNP gene transcription by inhibiting neuron-restrictive silencer element-dependent repression.
Cardiovasc Res. 53:451-459, 2002.