研究業績(2005.6〜)


2012

Naruse K, Noguchi T, Sado T, Tsunemi T, Shigetomi H, Kanayama S, Akasaka J, Koike N, Oi H, Kobayashi H. Chemokine and free Fatty Acid levels in insulin-resistant state of successful pregnancy: a preliminary observation. Mediators Inflamm. 2012;2012:432575.

Naruse K, Sado T, Noguchi T, Tsunemi T, Yoshida S, Akasaka J, Koike N, Oi H, Kobayashi H. Peripheral RAGE (receptor for advanced glycation endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response. J Reprod Immunol. 2012 Mar;93(2):69-74.

Nagai A, Sado T, Naruse K, Noguchi T, Haruta S, Yoshida S, Tanase Y, Tsunemi T, Kobayashi H. Antiangiogenic-induced hypertension: the molecular basis of signaling network. Gynecol Obstet Invest. 2012;73(2):89-98.

Koyama E, Naruse K, Shigetomi H, Sado T, Oi H, Kobayashi H. Combination of B-Lynch brace suture and uterine artery embolization for atonic bleeding after cesarean section in a patient with placenta previa accreta. J Obstet Gynaecol Res. 2012 Jan;38(1):345-8.

2011

Naruse K, Yamasaki Y, Tsunemi T, Onogi A, Noguchi T, Sado T, Oi H, Kobayashi H. Increase of high molecular weight adiponectin in hypertensive pregnancy was correlated with brain-type natriuretic peptide stimulation on adipocyte. Pregnancy Hypertension. 2011;1(3-4):200-205.

Haruta S, Furukawa N, Yoshizawa Y, Tsunemi T, Nagai A, Kawaguchi R, Tanase Y, Yoshida S, Kobayashi H. Molecular genetics and epidemiology of epithelial ovarian cancer (Review). Oncol Rep. 2011 Dec;26(6):1347-56.

Yamada Y, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Yoshida S, Furukawa N, Nagai A, Tanase Y, Tsunemi T, Oi H, Kobayashi H. Redox-active iron-induced oxidative stress in the pathogenesis of clear cell carcinoma of the ovary. Int J Gynecol Cancer. 2011 Oct;21(7):1200-7.

Lash GE, Naruse K, Robson A, Innes BA, Searle RF, Robson SC, Bulmer JN. Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production. Hum Reprod. 2011 Sep;26(9):2289-95.

Furukawa N, Kawaguchi R, Kobayashi H. Use of high-dose cisplatin with aprepitant in an outpatient setting. Eur J Cancer Care (Engl). 2011 Aug 25.

Kawaguchi R, Furukawa N, Yamada Y, Ooi H, Kobayashi H. Carcinosarcoma of the uterine corpus with alpha-fetoprotein-producing hepatoid adenocarcinoma: a report of two cases. Case Rep Oncol. 2011;4(2):358-62

Onogi A, Naruse K, Sado T, Tsunemi T, Shigetomi H, Noguchi T, Yamada Y, Akasaki M, Oi H, Kobayashi H. Hypoxia inhibits invasion of extravillous trophoblast cells through reduction of matrix metalloproteinase (MMP)-2 activation in the early first trimester of human pregnancy. Placenta. 2011 Sep;32(9):665-70

Yoshizawa Y, Yamada Y, Kanayama S, Shigetomi H, Kawaguchi R, Yoshida S, Nagai A, Furukawa N, Oi H, Kobayashi H. Signaling pathway involved in cyclooxygenase-2 up-regulation by hepatocyte growth factor in endometrial cancer cells. Oncol Rep. 2011 Oct;26(4):957-64.

Furukawa N, Kawaguchi R, Kajihara H, Kobayashi H. Evaluation of the vessels of the cardinal ligament by transrectal ultrasonography with color Doppler imaging. J Clin Ultrasound. 2011 Nov-Dec;39(9):502-5.

Sado T, Naruse K, Noguchi T, Haruta S, Yoshida S, Tanase Y, Kitanaka T, Oi H, Kobayashi H. Inflammatory pattern recognition receptors and their ligands: factors contributing to the pathogenesis of preeclampsia. Inflamm Res. 2011 Jun;60(6):509-20.

Sado T, Kitanaka T, Naruse K, Oi H, Noguchi T, Yoshida S, Kajihara H, Shigetomi H, Oonogi A, Kobayashi H. Anticytokine therapy in preterm labor: current knowledge and future perspectives. Gynecol Obstet Invest. 2011;71(1):1-10.

Mizutani S, Wright J, Kobayashi H. A new approach regarding the treatment of preeclampsia and preterm labor. Life Sci. 2011 Jan 3;88(1-2):17-23.

Mizutani S, Wright JW, Kobayashi H. Placental leucine aminopeptidase- and aminopeptidase A- deficient mice offer insight concerning the mechanisms underlying preterm labor and preeclampsia. J Biomed Biotechnol. 2011;2011:286947.

Otun HA, Lash GE, Innes BA, Bulmer JN, Naruse K, Hannon T, Searle RF, Robson SC. Effect of tumour necrosis factor-α in combination with interferon-γ on first trimester extravillous trophoblast invasion. J Reprod Immunol. 88(1):1-11.

Kobayashi H, Kajihara H, Yamada Y, Tanase Y, Kanayama S, Furukawa N, Noguchi T, Haruta S, Yoshida S, Naruse K, Sado T, Oi H. Risk of carcinoma in women with ovarian endometrioma. Front Biosci (Elite Ed). 2011 Jan 1;3:529-39.

Kajihara H, Yamada Y, Kanayama S, Furukawa N, Noguchi T, Haruta S, Yoshida S, Sado T, Oi H, Kobayashi H. New insights into the pathophysiology of endometriosis: from chronic inflammation to danger signal. Gynecol Endocrinol. 2011 Feb;27(2):73-9.

Yamada Y, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Yoshida S, Furukawa N, Nagai A, Tanase Y, Tsunemi T, Oi H, Kobayashi H. New insights into pattern recognition receptors and their ligands in gynecologic pathologies. Hum Immunol. 2011 Mar;72(3):213-8.

2010

Yaguchi C, Oi H, Kobayashi H, Miura K, Kanayama N. A case of intravenous leiomyomatosis with high levels of hyaluronan. J Obstet Gynaecol Res. 2010 Apr;36(2):454-8.

Kajihara H, Yamada Y, Kanayama S, Furukawa N, Noguchi T, Haruta S, Yoshida S, Sado T, Oi H, Kobayashi H. Clear cell carcinoma of the ovary: potential pathogenic mechanisms (Review). Oncol Rep. 2010 May;23(5):1193-203.

Oi H, Naruse K, Noguchi T, Sado T, Kimura S, Kanayama N, Terao T, Kobayashi H. Fatal factors of clinical manifestations and laboratory testing in patients with amniotic fluid embolism. Gynecol Obstet Invest. 2010;70(2):138-44.

Inoue S, Abe R, Kawaguchi M, Kobayashi H, Furuya H. Metoclopramide does not prolong duration of action of landiolol attenuating the hemodynamic response to induction of anesthesia and tracheal intubation. J Anesth. 2010 Aug;24(4):649-52.

Inoue S, Abe R, Kawaguchi M, Kobayashi H, Furuya H. Beta blocker infusion decreases the magnitude of core hypothermia after anesthesia induction. Minerva Anestesiol. 2010 Dec;76(12):1002-9.

Furukawa N, Takekuma M, Takahashi N, Hirashima Y. Intraoperative evaluation of myometrial invasion and histological type and grade in endometrial cancer: diagnostic value of frozen section. Arch Gynecol Obstet. 2010 May;281(5):913-7.

Shigemitsu A, Furukawa F, Koike N, Kobayashi H. Endometrial Cancer Diagnosed by the Presence of Bone Metastasis and Treated with Zoledronic Acid: A Case Report and Review of the Literature. Case Rep Oncol. 2010 3(3):471-476

Furukawa N, Oi H, Yoshida S, Shigetomi H,?Kanayama S, Kobayashi H. The usefulness of photodynamic eye for sentinel?lymph node identification in patients?with cervical cancer. Tumori. 2010;96(6):936- 940

Kobayashi H. Screening, epidemiology, molecular biology, and treatment strategies for endometriosis-associated ovarian cancer. Reprod Med Biol 2010;9:17-22

Shigetomi H, Onogi A, Kajiwara H, Yoshida S, Furukawa N, Haruta S, Tanase Y, Kanayama S, Noguchi T, Yamada Y, Oi H, Kobayashi H. Anti-inflammatory actions of serine protease inhibitors containing the Kunitz domain. Inflamm Res. 2010 Sep;59(9):679-87.

Naruse K, Innes BA, Bulmer JN, Robson SC, Searle RF, Lash GE. Secretion of cytokines by villous cytotrophoblast and extravillous trophoblast in the first trimester of human pregnancy. J Reprod Immunol. 86(2); 148-150

Lash GE, Naruse K, Innes BA, Robson SC, Searle RF, Bulmer JN.Secretion of angiogenic growth factors by villous cytotrophoblast and extravillous trophoblast in early human pregnancy. Placenta. 31(6); 545-548

Inoue S, Abe R, Kawaguchi M, Kobayashi H, Furuya H. Beta blocker infusion decreases the magnitude of core hypothermia after anesthesia induction. Minerva Anestesiol. 2010 Dec;76(12):1002-9.

Noguchi T, Sado T, Naruse K, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Nagai A, Tanase Y, Yoshida S, Kitanaka T, Oi H, Kobayashi H. Evidence for activation of Toll-like receptor and receptor for advanced glycation end products in preterm birth. Mediators Inflamm. 2010;2010:490406.

2009

Kobayashi H, Yamada Y, Kanayama S, Furukawa N, Noguchi T, Haruta S, Yoshida S, Sakata M, Sado T, Oi H. The role of iron in the pathogenesis of endometriosis. Gynecol Endocrinol. 2009 Jan;25(1):39-52.

Ishii M, Hattori A, Numaguchi Y, Ma X, Nagasaka T, Tsujimoto M, Murohara T, Kobayashi H, Mizutani S. The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs). Early Hum Dev. 2009;85(9):589-94

Kobayashi H, Yamada Y, Kanayama S, Furukawa N, Noguchi T, Haruta S, Yoshida S, Sakata M, Sado T, Oi H. The role of hepatocyte nuclear factor-1beta in the pathogenesis of clear cell carcinoma of the ovary. Int J Gynecol Cancer. 2009 Apr;19(3):471-9.

Kobayashi H, Kajiwara H, Kanayama S, Yamada Y, Furukawa N, Noguchi T, Haruta S, Yoshida S, Sakata M, Sado T, Oi H. Molecular pathogenesis of endometriosis-associated clear cell carcinoma of the ovary (review). Oncol Rep. 2009 Aug;22(2):233-40.

Shibata M, Kanehiro H, Shinkawa T, Fujita Y, Yada K, Kamamoto T, Arai I, Nishikubo T, Sakata M, Kobayashi H, Takeda M, Nonomura A, Takahashi Y. A neonate with umbilical arteriovenous malformation showing hemorrhagic shock from massive umbilical hemorrhage. Am J Perinatol. 2009 Sep;26(8):583-6.

Kobayashi H. Ovarian cancer in endometriosis: epidemiology, natural history, and clinical diagnosis. Int J Clin Oncol. 2009 Oct;14(5):378-82.

Naruse K, Lash GE, Innes BA, Otun HA, Searle RF, Robson SC, Bulmer JN. Localisation of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitors for MMPs (TIMPs) in uterine natural killer cells in early human pregnancy. Hum Reprod. 24 (3): 553-561

Yoshida S, Furukawa N, Haruta S, Tanase Y, Kanayama S, Noguchi T, Sakata M, Yamada Y, Oi H, Kobayashi H. Theoretical model of treatment strategies for clear cell carcinoma of the ovary: focus on perspectives. Cancer Treat Rev. 2009 Nov;35(7):608-15.

Ishii M, Naruse K, Hattori A, Tsujimoto M, Ishiura S, Numaguchi Y, Murohara T, Kobayashi H, Mizutani S. Oxytocin hypersensitivity in pregnant P-LAP deficient mice. Life Sci. 84; 668-672

Naruse K, Lash GE, Bulmer JN, Innes BA, Otun HA, Searle RF, Robson SC. The Urokinase Plasminogen Activator (uPA) System in Uterine Natural Killer Cells in the Placental Bed During Early Pregnancy. Placenta. 30(5):398-404

Yoshida S, Furukawa N, Haruta S, Tanase Y, Kanayama S, Noguchi T, Sakata M, Yamada Y, Oi H, Kobayashi H. Expression profiles of genes involved in poor prognosis of epithelial ovarian carcinoma: a review. Int J Gynecol Cancer. 2009 Aug;19(6):992-7.

2008

Kawaguchi R, Ueda S, Tsuji Y, Haruta S, Kanayama S, Yamada Y, Ooi H, Kobayashi H. Massive ovarian edema in pregnancy after ovulation induction using clomiphene citrate. Arch Gynecol Obstet. 2008 Apr;277(4):375-8.

Kobayashi H, Yamada Y, Sado T, Sakata M, Yoshida S, Kawaguchi R, Kanayama S, Shigetomi H, Haruta S, Tsuji Y, Ueda S, Kitanaka T, Oi H. Prevalence of Ovarian Cancer among Women with a CA125 Level of 35 U/ml or Less. Gynecol Obstet Invest. 2008;65(2):133-138

Kobayashi H, Yamada Y, Sado T, Sakata M, Yoshida S, Kawaguchi R, Kanayama S, Shigetomi H, Haruta S, Tsuji Y, Ueda S, Kitanaka T. A randomized study of screening for ovarian cancer: a multicenter study in Japan. Int J Gynecol Cancer. 2008 May-Jun;18(3):414-20.

Kobayashi H, Sumimoto K, Kitanaka T, Yamada Y, Sado T, Sakata M, Yoshida S, Kawaguchi R, Kanayama S, Shigetomi H, Haruta S, Tsuji Y, Ueda S, Terao T. Ovarian endometrioma--risks factors of ovarian cancer development. Eur J Obstet Gynecol Reprod Biol. 2008 Jun;138(2):187-93.

Kanayama S, Yamada Y, Kawaguchi R, Tsuji Y, Haruta S, Kobayashi H. Hepatocyte growth factor induces anoikis resistance by up-regulation of cyclooxygenase-2 expression in uterine endometrial cancer cells. Oncol Rep. 2008 Jan;19(1):117-22.

Ueda S, Yamada Y, Tsuji Y, Kawaguchi R, Haruta S, Shigetomi H, Kanayama S, Yoshida S, Sakata M, Sado T, Kitanaka K, Kobayashi H. Giant abdominal tumor of the ovary. J Obstet Gynaecol Res. 2008 Feb;34(1):108-11.

Kanayama S, Yamada Y, Onogi A, Shigetomi H, Ueda S, Tsuji Y, Haruta S, Kawaguchi R, Yoshida S, Sakata M, Sado T, Kitanaka T, Oi H, Yagyu T, Kobayashi H. Molecular structure and function analysis of bikunin on down-regulation of tumor necrosis factor-alpha expression in activated neutrophils. Cytokine. 2008 May;42(2):191-7.

Ishii M, Hattori A, Numaguchi Y, Tsujimoto M, Ishiura S, Kobayashi H, Murohara T, Wright JW, Mizutani S. The Effect of Recombinant Aminopeptidase A on Hypertension in Spontaneously Hypertensive Rats: Its Effect in Comparison with Candesartan. Horm Metab Res. 2008; 40(12):887-891

Mizutani S, Ishii M, Hattori A, Nomura S, Numaguchi Y, Tsujimoto M, Kobayashi H, Murohara T, Wright JW. New insights into the importance of aminopeptidase A in hypertension. Heart Fail. Rev. 2008;13:273-284

Matsuyama T, Komeda S, Nobayashi M, Imanishi M, Kawaguchi S. Acute gastric dilatation causing bacterial cerebral aneurysm--case report. Int J Eat Disord. 41(4):380-2.

Yoshida S, Onogi A, Shigetomi H, Tsuji Y, Haruta S, Naruse K, Kanayama S, Noguchi T, Sakata M, Furukawa N, Sado T, Yamada Y, Kitanaka T, Oi H, Kobayashi H. Two cases of pregnant women with ovarian endometrioma mimicking a malignant ovarian tumor. J Clin Ultrasound. 2008 Oct;36(8):512-6.

Sakata M, Sado T, Kitanaka T, Naruse K, Noguchi T, Yoshida S, Shigetomi H, Onogi A, Oi H, Kobayashi H. Iron-dependent oxidative stress as a pathogenesis for preterm birth. Obstet Gynecol Surv. 2008 Oct;63(10):651-60.

Takahashi N, Hirashima Y, Harashima S, Takekuma M, Kawaguchi R, Yamada Y, Ito I. A patient with stage 1a endometrial carcinoma in whom a solitary recurrent lesion was detected in the external iliac lymph node after MPA therapy. Arch Gynecol Obstet. 2008 Oct;278(4):365-7.

Kawaguchi R, Tsuji Y, Haruta S, Kanayama S, Sakata M, Yamada Y, Fujita H, Saito H, Tsuneto K, Kobayashi H. Clinicopathologic features of ovarian cancer in patients with ovarian endometrioma. J Obstet Gynaecol Res. 2008 Oct;34(5):872-7.

2007

Kobayashi H, Sumimoto K, Moniwa N, Imai M, Takakura K, Kuromaki T, Morioka E, Arisawa K, Terao T. Risk of developing ovarian cancer among women with ovarian endometrioma: a cohort study in Shizuoka, Japan. Int J Gynecol Cancer. 2007 Jan-Feb;17(1):37-43.

Mizutani S, Shibata K, Kikkawa F, Hattori A, Tsujimoto M, Ishii M, and Kobayashi H. Esssential role of placental leucine aminopeptidase in gynecologic malignancy. Expert Opin Ther Targets. 11(4): 453-461, 2007.

Kobayashi H, Ooi H, Yamada Y, Sakata M, Kawaguchi R, Kanayama S, Sumimoto K, Terao T. Serum CA125 level before the development of ovarian cancer. Int J Gynaecol Obstet. 2007 Nov;99(2):95-9.

Furukawa N. Solitary splenic metastasis of ovarian cancer. Arch Gynecol Obstet. 2007 Jun;275(6):499-502.

Tanase Y, Yamada T, Kawaryu Y, Yoshida M, Kawai S. A case of spontaneous pneumothorax during pregnancy and review of the literature. Kobe J Med Sci. 2007;53(5):251-5

Kobayashi H, Sumimoto K, Kitanaka T, Yamada Y, Sado T, Sakata M, Yoshida S, Kawaguchi R, Kanayama S, Shigetomi H, Haruta S, Tsuji Y, Ueda S, Terao T. Ovarian endometrioma-Risks factors of ovarian cancer development. Eur J Obstet Gynecol Reprod Biol. 2007 Dec 24

Tsuji Y, Kawaguchi R, Haruta S, Shigetomi H, Ueda S, Kanayama S, Yoshida S, Sakata M, Sado T, Yamada Y, Kitanaka K, Kobayashi H. Late onset of pulmonary embolism caused by lymphocyst following pelvic lymphadenectomy. J Obstet Gynaecol Res. 2007 Oct;33(5):734-8.

Sado T, Oi H, Sakata M, Yoshida S, Kawaguchi R, Kanayama S, Shigetomi H, Haruta S, Tsuji Y, Ueda S, Kitanaka T, Yamada Y, Kobayashi H. Aging impairs the protective effect of magnesium supplementation on hypertension in spontaneously hypertensive rats. Magnes Res. 2007 Sep;20(3):196-9.

Kanayama S, Yamada Y, Onogi A, Shigetomi H, Ueda S, Tsuji Y, Haruta S, Kawaguchi R, Yoshida S, Sakata M, Sado T, Kitanaka T, Oi H, Yagyu T, Kobayashi H. Bikunin suppresses expression of pro-inflammatory cytokines induced by lipopolysaccharide in neutrophils. J Endotoxin Res. 2007;13(6):369-76.

2006

Yagyu T, Kobayashi H, Matsuzaki H, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K. Enhanced spontaneous metastasis in bikunin-deficient mice. Int. J. Cancer. 118 (9): 2322-2328, 2006.

Yagyu T, Tsuji Y, Haruta S, Kitanaka T, Yamada Y, Kawaguchi R, Kanayama S, Tanase Y, Kurita N, and Kobayashi H. Activation of mammalian target of rapamycin in postmenopausal ovarian endometriosis. Int. J. Gynecol Cancer 16; 1545-1551, 2006.

Takekuma M, Hirashima Y, Takahashi N, Yamamichi G, Furukawa N, Yamada Y, Takakuwa R, Ito I. A case of glassy cell carcinoma of the uterine cervix that responded to neoadjuvant chemotherapy with paclitaxel and carboplatin. Anticancer Drugs. 2006 Jul;17(6):715-8.

Kobayashi H. Endogenous antiinflammatory substances: inter-alpha-inhibitor and bikunin. Biol. Chem. 387 (12); 1545-1549, 2006.

2005

Kobayashi H, Yagyu T, Kondo T, Kurita N, Inagaki K, Haruta S, Kawaguchi R, Kitanaka T, Sakamoto Y, Yamada Y, Kanayama N, Terao T. Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kappa B activation and subsequently suppressed ovarian cancer dissemination. Cancer Res. 65 (22): 10464-10471, 2005.

Kobayashi H, Yoshida T, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Yamada Y, Sado T, Kitanaka T, Suzuki M, Kanayama N, Terao T. A soybean Kunitz trypsin inhibitor reduces tumor necrosis factor-alpha production in ultraviolet-exposed primary human keratinocytes. Experimental Dermatol. 14 (10): 765-774, 2005.

Inagaki K, Kobayashi H, Yoshida Y, Kanada Y, Fukuda Y, Yagyu T, Kondo T, Kurita N, Kitanaka T, Yamada Y, Sakamoto Y, Suzuki M, Kanayama N, Terao T. Suppression of urokinase expression and invasion by a soybean trypsin inhibitor are mediated through inhibition of Src-dependent signaling pathways. J. Biol. Chem. 280 (36): 31428-31437, 2005.

To be continued...


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