Updated : October 6, 2020

Molecular Oncological Pathology

Supervisor

Hiroki Kuniyasu (Professor)

Specialized Subjects

Pathology plays a pivotal role in bench to bedside by the application of diagnostic and therapeutic cues obtained in the examination of disease mechanisms using cutting edge methodologies, which is the essence of pathology from the creation by Virchow. Despite passage of time, the fundamental principles of pathology remain unchanged. The importance of pathology has increased with the rapidly aging society. In the Department of Molecular Oncological Pathology, the two most important health disorders, cancer and diabetes, are studied to clarify the cause, mechanism, methods of prevention, and progression of these disorders, and to identify novel markers for high risk and high malignant potential and molecular targets for treatments. Furthermore, evaluation of novel markers and therapeutic targets by examination of histopathological materials is performed to enhance the clinical application of novel trials. We focus on metabolism as a target for cancer treatment through short- and long-term projects, which should be objected in parallel. Through communication with mentors and fellow students, scientific knowledge, logical thinking, critical evaluation of data, and interest in unearthing unknown information will be enhanced, which may lead to a breakthrough in this field of research.
Subjects:
1. Effect of dietary components on cancer development and progression
2. Relationship between host metabolic status and cancer progression
3. Exploration and targeting of cancer-specific metabolism
4. Prediction and prevention of cancer metastasis
5. Relationship between symbiotic microorganisms and cancer
6. Advisable dietary habit for cancer-burden persons